U01 NS092495/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	1
2017	1
2018	3
2019	3
2020	4
2021	1
2024	1

1

[¹¹C]Paraoxon: Radiosynthesis, Biodistribution and In Vivo Positron Emission Tomography Imaging in Rat.

Hayes TR, Chao CK, Blecha JE, Huynh TL, VanBrocklin HF, Zinn KR, Gerdes JM, Thompson CM. Hayes TR, et al. J Pharmacol Exp Ther. 2024 Jan 17;388(2):333-346. doi: 10.1124/jpet.123.001832. J Pharmacol Exp Ther. 2024. PMID: 37770203 Free PMC article.

2

Biological Distribution and Metabolic Profiles of Carbon-11 and Fluorine-18 Tracers of VX- and Sarin-Analogs in Sprague-Dawley Rats.

Hayes TR, Chao CK, Blecha JE, Huynh TL, Zinn KR, Thompson CM, Gerdes JM, VanBrocklin HF. Hayes TR, et al. Chem Res Toxicol. 2021 Jan 18;34(1):63-69. doi: 10.1021/acs.chemrestox.0c00237. Epub 2020 Dec 29. Chem Res Toxicol. 2021. PMID: 33373198 Free PMC article.

3

Inhibition of Acetylcholinesterases by Stereoisomeric Organophosphorus Compounds Containing Both Thioester and p-Nitrophenyl Leaving Groups.

Talley TT, Chao CK, Berkman CE, Richardson RJ, Thompson CM. Talley TT, et al. Chem Res Toxicol. 2020 Sep 21;33(9):2455-2466. doi: 10.1021/acs.chemrestox.0c00236. Epub 2020 Sep 9. Chem Res Toxicol. 2020. PMID: 32833441

4

Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[¹⁸ F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [¹⁸ F]-VXS.

Hayes TR, Blecha JE, Chao CK, Huynh TL, VanBrocklin HF, Zinn KR, Taylor PW, Gerdes JM, Thompson CM. Hayes TR, et al. Ann N Y Acad Sci. 2020 Nov;1479(1):180-195. doi: 10.1111/nyas.14363. Epub 2020 May 20. Ann N Y Acad Sci. 2020. PMID: 32436233 Free PMC article.

5

Comparison of the reactivation rates of acetylcholinesterase modified by structurally different organophosphates using novel pyridinium oximes.

Bharate SB, Chao CK, Thompson CM. Bharate SB, et al. Environ Toxicol Pharmacol. 2019 Oct;71:103218. doi: 10.1016/j.etap.2019.103218. Epub 2019 Jul 5. Environ Toxicol Pharmacol. 2019. PMID: 31302432 Free PMC article.

6

Divergent synthesis of organophosphate [¹¹C]VX- and [¹¹C]Sarin-surrogates from a common set of starting materials.

Hayes TR, Blecha JE, Thompson CM, Gerdes JM, VanBrocklin HF. Hayes TR, et al. Appl Radiat Isot. 2019 Sep;151:182-186. doi: 10.1016/j.apradiso.2019.05.033. Epub 2019 May 24. Appl Radiat Isot. 2019. PMID: 31202183 Free PMC article.

7

Positron emission tomography studies of organophosphate chemical threats and oxime countermeasures.

Thompson CM, Gerdes JM, VanBrocklin HF. Thompson CM, et al. Neurobiol Dis. 2020 Jan;133:104455. doi: 10.1016/j.nbd.2019.04.011. Epub 2019 Apr 22. Neurobiol Dis. 2020. PMID: 31022458 Free PMC article. Review.

8

Radiosynthesis of O-(1-[¹⁸ F]fluoropropan-2-yl)-O-(4-nitrophenyl)methylphosphonate: A novel PET tracer surrogate of sarin.

Hayes TR, Thompson CM, Blecha JE, Gerdes JM, VanBrocklin HF. Hayes TR, et al. J Labelled Comp Radiopharm. 2018 Dec;61(14):1089-1094. doi: 10.1002/jlcr.3688. Epub 2018 Nov 4. J Labelled Comp Radiopharm. 2018. PMID: 30347484 Free PMC article.

9

Radiosynthesis, ex Vivo Biodistribution, and in Vivo Positron Emission Tomography Imaging Evaluations of [¹¹C]2-Pyridinealdoxime Methiodide ([¹¹C]2-PAM): A First-In-Class Antidote Tracer for Organophosphate Intoxication.

Neumann KD, Blecha JE, Hayes TR, Huynh T, Chao CK, Guilloteau N, Zinn KR, VanBrocklin HF, Thompson CM, Gerdes JM. Neumann KD, et al. ACS Chem Neurosci. 2018 Dec 19;9(12):3007-3014. doi: 10.1021/acschemneuro.8b00212. Epub 2018 Aug 20. ACS Chem Neurosci. 2018. PMID: 30071719 Free PMC article.

10

The inhibition, reactivation and mechanism of VX-, sarin-, fluoro-VX and fluoro-sarin surrogates following their interaction with HuAChE and HuBuChE.

Chao CK, Balasubramanian N, Gerdes JM, Thompson CM. Chao CK, et al. Chem Biol Interact. 2018 Aug 1;291:220-227. doi: 10.1016/j.cbi.2018.06.019. Epub 2018 Jun 18. Chem Biol Interact. 2018. PMID: 29920286 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

12 results

Results by year

Search Page

Filters

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

Search Results

12 results

Results by year