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Epigenetically induced ectopic expression of UNCX impairs the proliferation and differentiation of myeloid cells.
Daniele G, Simonetti G, Fusilli C, Iacobucci I, Lonoce A, Palazzo A, Lomiento M, Mammoli F, Marsano RM, Marasco E, Mantovani V, Quentmeier H, Drexler HG, Ding J, Palumbo O, Carella M, Nadarajah N, Perricone M, Ottaviani E, Baldazzi C, Testoni N, Papayannidis C, Ferrari S, Mazza T, Martinelli G, Storlazzi CT. Daniele G, et al. Haematologica. 2017 Jul;102(7):1204-1214. doi: 10.3324/haematol.2016.163022. Epub 2017 Apr 14. Haematologica. 2017. PMID: 28411256 Free PMC article.
UNCX expression turned out to be associated, and significantly correlated, with DNA methylation increase at its canyon borders based on data in our patients and in archived data of patients from The Cancer Genome Atlas. UNCX-positive and -negative patients di …
UNCX expression turned out to be associated, and significantly correlated, with DNA methylation increase at its canyon borders based …
DNA methylation clocks for clawed frogs reveal evolutionary conservation of epigenetic aging.
Zoller JA, Parasyraki E, Lu AT, Haghani A, Niehrs C, Horvath S. Zoller JA, et al. Geroscience. 2024 Feb;46(1):945-960. doi: 10.1007/s11357-023-00840-3. Epub 2023 Jun 4. Geroscience. 2024. PMID: 37270437 Free PMC article.
Highly conserved positively age-related CpGs are located in neural-developmental genes such as uncx, tfap2d as well as nr4a2 implicated in age-associated disease. ...
Highly conserved positively age-related CpGs are located in neural-developmental genes such as uncx, tfap2d as well as nr4a2 implicat …
A Panel of Novel Detection and Prognostic Methylated DNA Markers in Primary Non-Small Cell Lung Cancer and Serum DNA.
Ooki A, Maleki Z, Tsay JJ, Goparaju C, Brait M, Turaga N, Nam HS, Rom WN, Pass HI, Sidransky D, Guerrero-Preston R, Hoque MO. Ooki A, et al. Clin Cancer Res. 2017 Nov 15;23(22):7141-7152. doi: 10.1158/1078-0432.CCR-17-1222. Epub 2017 Aug 29. Clin Cancer Res. 2017. PMID: 28855354
Purpose: To establish a novel panel of cancer-specific methylated genes for cancer detection and prognostic stratification of early-stage non-small cell lung cancer (NSCLC).Experimental Design: Identification of differentially methylated regions (DMR) was per …
Purpose: To establish a novel panel of cancer-specific methylated genes for cancer detection and prognostic stratification of …
Detection of Missing Proteins Using the PRIDE Database as a Source of Mass Spectrometry Evidence.
Garin-Muga A, Odriozola L, Martínez-Val A, Del Toro N, Martínez R, Molina M, Cantero L, Rivera R, Garrido N, Dominguez F, Sanchez Del Pino MM, Vizcaíno JA, Corrales FJ, Segura V. Garin-Muga A, et al. J Proteome Res. 2016 Nov 4;15(11):4101-4115. doi: 10.1021/acs.jproteome.6b00437. Epub 2016 Sep 15. J Proteome Res. 2016. PMID: 27581094 Free PMC article.
As illustrative examples, DNAH3 and TEPP in spermatozoa, and UNCX and ATAD3C in HEK293 cells were some of the more robust and remarkable identifications in this study. ...
As illustrative examples, DNAH3 and TEPP in spermatozoa, and UNCX and ATAD3C in HEK293 cells were some of the more robust and remarka …