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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1993 2
1994 1
1995 2
1997 1
1998 2
1999 1
2000 3
2001 2
2002 1
2003 1
2004 3
2005 5
2006 5
2007 2
2008 6
2009 3
2010 5
2011 5
2012 7
2013 6
2014 3
2015 9
2016 5
2017 2
2018 9
2019 14
2020 4
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2024 6

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123 results

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Page 1
Comprehensive Analysis Reveals USP45 as a Novel Putative Oncogene in Pan-Cancer.
Li K, Wang Q, Bian H, Chen Z, He H, Zhao X, Gong P. Li K, et al. Front Mol Biosci. 2022 Jun 28;9:886904. doi: 10.3389/fmolb.2022.886904. eCollection 2022. Front Mol Biosci. 2022. PMID: 35836933 Free PMC article.
At last, the protein expression levels of USP45 were detected by immunohistochemistry in tumor tissue microarrays. ...Finally, we constructed the ceRNA regulatory network, protein-protein interaction network and downstream regulatory network for USP45 in different t …
At last, the protein expression levels of USP45 were detected by immunohistochemistry in tumor tissue microarrays. ...Finally, we con …
USP45 and Spindly are part of the same complex implicated in cell migration.
Conte C, Griffis ER, Hickson I, Perez-Oliva AB. Conte C, et al. Sci Rep. 2018 Sep 26;8(1):14375. doi: 10.1038/s41598-018-32685-8. Sci Rep. 2018. PMID: 30258100 Free PMC article.
Here, by using mass spectrometry we have identified Spindly as a new target of USP45. Our data show that Spindly and USP45 are part of the same complex and that their interaction specifically depends on the catalytic activity of USP45. ...Lastly, we identifie …
Here, by using mass spectrometry we have identified Spindly as a new target of USP45. Our data show that Spindly and USP45 are …
USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses.
Perez-Oliva AB, Lachaud C, Szyniarowski P, Muñoz I, Macartney T, Hickson I, Rouse J, Alessi DR. Perez-Oliva AB, et al. EMBO J. 2015 Feb 3;34(3):326-43. doi: 10.15252/embj.201489184. Epub 2014 Dec 23. EMBO J. 2015. PMID: 25538220 Free PMC article.
Reversible protein ubiquitylation plays important roles in various processes including DNA repair. Here, we identify the deubiquitylase USP45 as a critical DNA repair regulator. USP45 associates with ERCC1, a subunit of the DNA repair endonuclease XPF-ERCC1, via a s …
Reversible protein ubiquitylation plays important roles in various processes including DNA repair. Here, we identify the deubiquitylase U …
Biallelic mutations in USP45, encoding a deubiquitinating enzyme, are associated with Leber congenital amaurosis.
Yi Z, Ouyang J, Sun W, Xiao X, Li S, Jia X, Wang P, Zhang Q. Yi Z, et al. J Med Genet. 2019 May;56(5):325-331. doi: 10.1136/jmedgenet-2018-105709. Epub 2018 Dec 20. J Med Genet. 2019. PMID: 30573563
The knockdown of usp45 transcript in zebrafish led to abnormal retinal development with effects on photoreceptors, which could be successfully rescued by wild-type usp45 mRNA. ...CONCLUSIONS: Our study implicates that biallelic mutations in USP45 are associat …
The knockdown of usp45 transcript in zebrafish led to abnormal retinal development with effects on photoreceptors, which could be suc …
Another Breaker of the Wall: the Biological Function of the Usp45 Protein of Lactococcus lactis.
Hernandez-Valdes JA, Huang C, Kok J, Kuipers OP. Hernandez-Valdes JA, et al. Appl Environ Microbiol. 2020 Aug 3;86(16):e00903-20. doi: 10.1128/AEM.00903-20. Print 2020 Aug 3. Appl Environ Microbiol. 2020. PMID: 32532874 Free PMC article.
However, the biological function of Usp45 has remained obscure despite more than 25 years of research. Studies on Usp45 homologs in other Gram-positive bacteria suggest that Usp45 may play a role in cell wall turnover processes. ...
However, the biological function of Usp45 has remained obscure despite more than 25 years of research. Studies on Usp45 homolo …
Holin-assisted bacterial recombinant protein export.
Guo T, Cui Y, Zhang L, Xu X, Xu Z, Kong J. Guo T, et al. Biotechnol Bioeng. 2022 Oct;119(10):2908-2918. doi: 10.1002/bit.28179. Epub 2022 Jul 28. Biotechnol Bioeng. 2022. PMID: 35822237
However, the overexpressed Hol380 could not release cytosolic proteins across the membrane in L. lactis NZ9000, but increased the secretory production of staphylococcal nuclease to 2.55-fold and fimbrial adhesin FaeG to 2.40-fold compared with those guided by signal peptide Us …
However, the overexpressed Hol380 could not release cytosolic proteins across the membrane in L. lactis NZ9000, but increased the secretory …
Secretion of recombinant xylanase in Lactococcus lactis using signal peptides Usp45 and Spk1.
Roslan AM, Mustafa Kamil A, Chandran C, Song AA, Yusoff K, Abdul Rahim R. Roslan AM, et al. Biotechnol Lett. 2020 Sep;42(9):1727-1733. doi: 10.1007/s10529-020-02894-1. Epub 2020 Apr 25. Biotechnol Lett. 2020. PMID: 32335791
OBJECTIVE: The effect of two signal peptides, namely Usp45 and Spk1 on the secretion of xylanase in Lactococcus lactis was analysed. ...CONCLUSION: Although Usp45 is the most commonly used signal peptide when secreting heterologous proteins in Lactococcus lactis, th …
OBJECTIVE: The effect of two signal peptides, namely Usp45 and Spk1 on the secretion of xylanase in Lactococcus lactis was analysed. …
Suppression of Cancer Cell Stemness and Drug Resistance via MYC Destabilization by Deubiquitinase USP45 Inhibition with a Natural Small Molecule.
Tu X, Li C, Sun W, Tian X, Li Q, Wang S, Ding X, Huang Z. Tu X, et al. Cancers (Basel). 2023 Feb 1;15(3):930. doi: 10.3390/cancers15030930. Cancers (Basel). 2023. PMID: 36765885 Free PMC article.
Interestingly, without enhancing cancer development, MYC silencing with shRNA can only suppress USP45-induced stemness and drug resistance. Moreover, we have identified that USP45 can be specifically bound and inhibited by a natural small molecule (alpha-mangostin), …
Interestingly, without enhancing cancer development, MYC silencing with shRNA can only suppress USP45-induced stemness and drug resis …
123 results