Uchida S - Search Results

1

Generation and analysis of the thiazide-sensitive Na+ -Cl- cotransporter (Ncc/Slc12a3) Ser707X knockin mouse as a model of Gitelman syndrome.

Yang SS, Lo YF, Yu IS, Lin SW, Chang TH, Hsu YJ, Chao TK, Sytwu HK, Uchida S, Sasaki S, Lin SH. Yang SS, et al. Among authors: uchida s. Hum Mutat. 2010 Dec;31(12):1304-15. doi: 10.1002/humu.21364. Epub 2010 Oct 14. Hum Mutat. 2010. PMID: 20848653

2

Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure.

Ohta A, Rai T, Yui N, Chiga M, Yang SS, Lin SH, Sohara E, Sasaki S, Uchida S. Ohta A, et al. Among authors: uchida s. Hum Mol Genet. 2009 Oct 15;18(20):3978-86. doi: 10.1093/hmg/ddp344. Epub 2009 Jul 24. Hum Mol Genet. 2009. PMID: 19633012

3

Mechanisms for hypercalciuria in pseudohypoaldosteronism type II-causing WNK4 knock-in mice.

Yang SS, Hsu YJ, Chiga M, Rai T, Sasaki S, Uchida S, Lin SH. Yang SS, et al. Among authors: uchida s. Endocrinology. 2010 Apr;151(4):1829-36. doi: 10.1210/en.2009-0951. Epub 2010 Feb 24. Endocrinology. 2010. PMID: 20181799

4

SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction.

Yang SS, Lo YF, Wu CC, Lin SW, Yeh CJ, Chu P, Sytwu HK, Uchida S, Sasaki S, Lin SH. Yang SS, et al. Among authors: uchida s. J Am Soc Nephrol. 2010 Nov;21(11):1868-77. doi: 10.1681/ASN.2009121295. Epub 2010 Sep 2. J Am Soc Nephrol. 2010. PMID: 20813865 Free PMC article.

5

Impaired phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndrome.

Lin SH, Yu IS, Jiang ST, Lin SW, Chu P, Chen A, Sytwu HK, Sohara E, Uchida S, Sasaki S, Yang SS. Lin SH, et al. Among authors: uchida s. Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17538-43. doi: 10.1073/pnas.1107452108. Epub 2011 Oct 4. Proc Natl Acad Sci U S A. 2011. PMID: 21972418 Free PMC article.

6

Phosphorylation regulates NCC stability and transporter activity in vivo.

Yang SS, Fang YW, Tseng MH, Chu PY, Yu IS, Wu HC, Lin SW, Chau T, Uchida S, Sasaki S, Lin YF, Sytwu HK, Lin SH. Yang SS, et al. Among authors: uchida s. J Am Soc Nephrol. 2013 Oct;24(10):1587-97. doi: 10.1681/ASN.2012070742. Epub 2013 Jul 5. J Am Soc Nephrol. 2013. PMID: 23833262 Free PMC article.

7

Function of chloride channels in the kidney.

Uchida S, Sasaki S. Uchida S, et al. Annu Rev Physiol. 2005;67:759-78. doi: 10.1146/annurev.physiol.67.032003.153547. Annu Rev Physiol. 2005. PMID: 15709977 Review.

8

Regulation of apical localization of the thiazide-sensitive NaCl cotransporter by WNK4 in polarized epithelial cells.

Yang SS, Yamauchi K, Rai T, Hiyama A, Sohara E, Suzuki T, Itoh T, Suda S, Sasaki S, Uchida S. Yang SS, et al. Among authors: uchida s. Biochem Biophys Res Commun. 2005 May 6;330(2):410-4. doi: 10.1016/j.bbrc.2005.02.172. Biochem Biophys Res Commun. 2005. PMID: 15796898

9

Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model.

Yang SS, Morimoto T, Rai T, Chiga M, Sohara E, Ohno M, Uchida K, Lin SH, Moriguchi T, Shibuya H, Kondo Y, Sasaki S, Uchida S. Yang SS, et al. Among authors: uchida k, uchida s. Cell Metab. 2007 May;5(5):331-44. doi: 10.1016/j.cmet.2007.03.009. Cell Metab. 2007. PMID: 17488636 Free article.

10

Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone.

Chiga M, Rai T, Yang SS, Ohta A, Takizawa T, Sasaki S, Uchida S. Chiga M, et al. Among authors: uchida s. Kidney Int. 2008 Dec;74(11):1403-9. doi: 10.1038/ki.2008.451. Epub 2008 Sep 17. Kidney Int. 2008. PMID: 18800028 Free article.

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