Ugalde AP - Search Results

1

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.

Varela I, Pereira S, Ugalde AP, Navarro CL, Suárez MF, Cau P, Cadiñanos J, Osorio FG, Foray N, Cobo J, de Carlos F, Lévy N, Freije JM, López-Otín C. Varela I, et al. Among authors: ugalde ap. Nat Med. 2008 Jul;14(7):767-72. doi: 10.1038/nm1786. Epub 2008 Jun 29. Nat Med. 2008. PMID: 18587406

2

Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function.

Mariño G, Ugalde AP, Fernández AF, Osorio FG, Fueyo A, Freije JM, López-Otín C. Mariño G, et al. Among authors: ugalde ap. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16268-73. doi: 10.1073/pnas.1002696107. Epub 2010 Aug 30. Proc Natl Acad Sci U S A. 2010. PMID: 20805469 Free PMC article.

3

Nuclear envelope defects cause stem cell dysfunction in premature-aging mice.

Espada J, Varela I, Flores I, Ugalde AP, Cadiñanos J, Pendás AM, Stewart CL, Tryggvason K, Blasco MA, Freije JM, López-Otín C. Espada J, et al. Among authors: ugalde ap. J Cell Biol. 2008 Apr 7;181(1):27-35. doi: 10.1083/jcb.200801096. Epub 2008 Mar 31. J Cell Biol. 2008. PMID: 18378773 Free PMC article.

4

Premature aging in mice activates a systemic metabolic response involving autophagy induction.

Mariño G, Ugalde AP, Salvador-Montoliu N, Varela I, Quirós PM, Cadiñanos J, van der Pluijm I, Freije JM, López-Otín C. Mariño G, et al. Among authors: ugalde ap. Hum Mol Genet. 2008 Jul 15;17(14):2196-211. doi: 10.1093/hmg/ddn120. Epub 2008 Apr 28. Hum Mol Genet. 2008. PMID: 18443001

5

Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging?

Ugalde AP, Mariño G, López-Otín C. Ugalde AP, et al. Aging (Albany NY). 2010 Dec;2(12):1017-22. doi: 10.18632/aging.100262. Aging (Albany NY). 2010. PMID: 21212467 Free PMC article.

6

Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53.

Ugalde AP, Ramsay AJ, de la Rosa J, Varela I, Mariño G, Cadiñanos J, Lu J, Freije JM, López-Otín C. Ugalde AP, et al. EMBO J. 2011 Jun 1;30(11):2219-32. doi: 10.1038/emboj.2011.124. Epub 2011 Apr 26. EMBO J. 2011. PMID: 21522133 Free PMC article.

7

Micromanaging aging with miRNAs: new messages from the nuclear envelope.

Ugalde AP, Español Y, López-Otín C. Ugalde AP, et al. Nucleus. 2011 Nov-Dec;2(6):549-55. doi: 10.4161/nucl.2.6.17986. Epub 2011 Nov 1. Nucleus. 2011. PMID: 22064465 Review.

8

Cell autonomous and systemic factors in progeria development.

Osorio FG, Ugalde AP, Mariño G, Puente XS, Freije JM, López-Otín C. Osorio FG, et al. Among authors: ugalde ap. Biochem Soc Trans. 2011 Dec;39(6):1710-4. doi: 10.1042/BST20110677. Biochem Soc Trans. 2011. PMID: 22103512 Review.

9

Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasion.

de la Rosa J, Freije JM, Cabanillas R, Osorio FG, Fraga MF, Fernández-García MS, Rad R, Fanjul V, Ugalde AP, Liang Q, Prosser HM, Bradley A, Cadiñanos J, López-Otín C. de la Rosa J, et al. Among authors: ugalde ap. Nat Commun. 2013;4:2268. doi: 10.1038/ncomms3268. Nat Commun. 2013. PMID: 23917225 Free PMC article.

10

Identification of human aminopeptidase O, a novel metalloprotease with structural similarity to aminopeptidase B and leukotriene A4 hydrolase.

Díaz-Perales A, Quesada V, Sánchez LM, Ugalde AP, Suárez MF, Fueyo A, López-Otín C. Díaz-Perales A, et al. Among authors: ugalde ap. J Biol Chem. 2005 Apr 8;280(14):14310-7. doi: 10.1074/jbc.M413222200. Epub 2005 Feb 1. J Biol Chem. 2005. PMID: 15687497 Free article. Retracted.

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