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KCNH2 encodes a nuclear-targeted polypeptide that mediates hERG1 channel gating and expression.
Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2214700120. doi: 10.1073/pnas.2214700120. Epub 2023 Jan 10.
Proc Natl Acad Sci U S A. 2023.
PMID: 36626562
Free PMC article.
hERG1 channel subunit composition mediates proton inhibition of rapid delayed rectifier potassium current (IKr) in cardiomyocytes derived from hiPSCs.
Ukachukwu CU, Jimenez-Vazquez EN, Jain A, Jones DK.
Ukachukwu CU, et al.
J Biol Chem. 2023 Feb;299(2):102778. doi: 10.1016/j.jbc.2022.102778. Epub 2022 Dec 8.
J Biol Chem. 2023.
PMID: 36496073
Free PMC article.
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Metal ion coordination in the E. coli Nudix hydrolase dihydroneopterin triphosphate pyrophosphatase: New clues into catalytic mechanism.
Hill SE, Nguyen E, Ukachukwu CU, Freeman DM, Quirk S, Lieberman RL.
Hill SE, et al. Among authors: ukachukwu cu.
PLoS One. 2017 Jul 25;12(7):e0180241. doi: 10.1371/journal.pone.0180241. eCollection 2017.
PLoS One. 2017.
PMID: 28742822
Free PMC article.
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Enzymatic hydrolysis by transition-metal-dependent nucleophilic aromatic substitution.
Kalyoncu S, Heaner DP Jr, Kurt Z, Bethel CM, Ukachukwu CU, Chakravarthy S, Spain JC, Lieberman RL.
Kalyoncu S, et al. Among authors: ukachukwu cu.
Nat Chem Biol. 2016 Dec;12(12):1031-1036. doi: 10.1038/nchembio.2191. Epub 2016 Oct 3.
Nat Chem Biol. 2016.
PMID: 27694799
Free PMC article.
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