Ulanovskaya O - Search Results

1

ABHD12 and LPCAT3 Interplay Regulates a Lyso-phosphatidylserine-C20:4 Phosphatidylserine Lipid Network Implicated in Neurological Disease.

Ichu TA, Reed A, Ogasawara D, Ulanovskaya O, Roberts A, Aguirre CA, Bar-Peled L, Gao J, Germain J, Barbas S, Masuda K, Conti B, Tontonoz P, Cravatt BF. Ichu TA, et al. Among authors: ulanovskaya o. Biochemistry. 2020 May 19;59(19):1793-1799. doi: 10.1021/acs.biochem.0c00292. Epub 2020 May 4. Biochemistry. 2020. PMID: 32364701 Free PMC article.

2

Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo.

Ogasawara D, Ichu TA, Vartabedian VF, Benthuysen J, Jing H, Reed A, Ulanovskaya OA, Hulce JJ, Roberts A, Brown S, Rosen H, Teijaro JR, Cravatt BF. Ogasawara D, et al. Among authors: ulanovskaya oa. Nat Chem Biol. 2018 Dec;14(12):1099-1108. doi: 10.1038/s41589-018-0155-8. Epub 2018 Nov 12. Nat Chem Biol. 2018. PMID: 30420694 Free PMC article.

3

Discovery and Optimization of Selective and in Vivo Active Inhibitors of the Lysophosphatidylserine Lipase α/β-Hydrolase Domain-Containing 12 (ABHD12).

Ogasawara D, Ichu TA, Jing H, Hulce JJ, Reed A, Ulanovskaya OA, Cravatt BF. Ogasawara D, et al. Among authors: ulanovskaya oa. J Med Chem. 2019 Feb 14;62(3):1643-1656. doi: 10.1021/acs.jmedchem.8b01958. Epub 2019 Feb 5. J Med Chem. 2019. PMID: 30720278 Free PMC article.

4

Phospholipase Cγ2 regulates endocannabinoid and eicosanoid networks in innate immune cells.

Jing H, Reed A, Ulanovskaya OA, Grigoleit JS, Herbst DM, Henry CL, Li H, Barbas S, Germain J, Masuda K, Cravatt BF. Jing H, et al. Among authors: ulanovskaya oa. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2112971118. doi: 10.1073/pnas.2112971118. Proc Natl Acad Sci U S A. 2021. PMID: 34607960 Free PMC article.

5

NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink.

Ulanovskaya OA, Zuhl AM, Cravatt BF. Ulanovskaya OA, et al. Nat Chem Biol. 2013 May;9(5):300-6. doi: 10.1038/nchembio.1204. Epub 2013 Mar 3. Nat Chem Biol. 2013. PMID: 23455543 Free PMC article.

6

Covalent inhibitors of nicotinamide N-methyltransferase (NNMT) provide evidence for target engagement challenges in situ.

Lee HY, Suciu RM, Horning BD, Vinogradova EV, Ulanovskaya OA, Cravatt BF. Lee HY, et al. Among authors: ulanovskaya oa. Bioorg Med Chem Lett. 2018 Sep 1;28(16):2682-2687. doi: 10.1016/j.bmcl.2018.04.017. Epub 2018 Apr 10. Bioorg Med Chem Lett. 2018. PMID: 29731364

7

Steady-state hydrogen peroxide induces glycolysis in Staphylococcus aureus and Pseudomonas aeruginosa.

Deng X, Liang H, Ulanovskaya OA, Ji Q, Zhou T, Sun F, Lu Z, Hutchison AL, Lan L, Wu M, Cravatt BF, He C. Deng X, et al. Among authors: ulanovskaya oa. J Bacteriol. 2014 Jul;196(14):2499-513. doi: 10.1128/JB.01538-14. Epub 2014 Apr 25. J Bacteriol. 2014. PMID: 24769698 Free PMC article.

8

Chemical Proteomic Profiling of Human Methyltransferases.

Horning BD, Suciu RM, Ghadiri DA, Ulanovskaya OA, Matthews ML, Lum KM, Backus KM, Brown SJ, Rosen H, Cravatt BF. Horning BD, et al. Among authors: ulanovskaya oa. J Am Chem Soc. 2016 Oct 12;138(40):13335-13343. doi: 10.1021/jacs.6b07830. Epub 2016 Sep 30. J Am Chem Soc. 2016. PMID: 27689866 Free PMC article.

9

Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria.

Deng X, Weerapana E, Ulanovskaya O, Sun F, Liang H, Ji Q, Ye Y, Fu Y, Zhou L, Li J, Zhang H, Wang C, Alvarez S, Hicks LM, Lan L, Wu M, Cravatt BF, He C. Deng X, et al. Among authors: ulanovskaya o. Cell Host Microbe. 2013 Mar 13;13(3):358-70. doi: 10.1016/j.chom.2013.02.004. Cell Host Microbe. 2013. PMID: 23498960 Free PMC article.

10

Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide.

Ulanovskaya OA, Janjic J, Suzuki M, Sabharwal SS, Schumacker PT, Kron SJ, Kozmin SA. Ulanovskaya OA, et al. Nat Chem Biol. 2008 Jul;4(7):418-24. doi: 10.1038/nchembio.94. Epub 2008 May 30. Nat Chem Biol. 2008. PMID: 18516048 Free PMC article.

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