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Phenotypic features of genetically modified DMD-XKOXWT pigs.
Okamoto K, Matsunari H, Nakano K, Umeyama K, Hasegawa K, Uchikura A, Takayanagi S, Watanabe M, Ohgane J, Stirm M, Kurome M, Klymiuk N, Nagaya M, Wolf E, Nagashima H. Okamoto K, et al. Among authors: umeyama k. Regen Ther. 2023 Sep 20;24:451-458. doi: 10.1016/j.reth.2023.09.010. eCollection 2023 Dec. Regen Ther. 2023. PMID: 37772130 Free PMC article.
Phenotypic features of dystrophin gene knockout pigs harboring a human artificial chromosome containing the entire dystrophin gene.
Watanabe M, Miyamoto H, Okamoto K, Nakano K, Matsunari H, Kazuki K, Hasegawa K, Uchikura A, Takayanagi S, Umeyama K, Hiramuki Y, Kemter E, Klymuik N, Kurome M, Kessler B, Wolf E, Kazuki Y, Nagashima H. Watanabe M, et al. Among authors: umeyama k. Mol Ther Nucleic Acids. 2023 Jul 23;33:444-453. doi: 10.1016/j.omtn.2023.07.021. eCollection 2023 Sep 12. Mol Ther Nucleic Acids. 2023. PMID: 37588685 Free PMC article.
Phototoxicity avoidance is a potential therapeutic approach for retinal dystrophy caused by EYS dysfunction.
Otsuka Y, Imamura K, Oishi A, Asakawa K, Kondo T, Nakai R, Suga M, Inoue I, Sagara Y, Tsukita K, Teranaka K, Nishimura Y, Watanabe A, Umeyama K, Okushima N, Mitani K, Nagashima H, Kawakami K, Muguruma K, Tsujikawa A, Inoue H. Otsuka Y, et al. Among authors: umeyama k. JCI Insight. 2024 Apr 22;9(8):e174179. doi: 10.1172/jci.insight.174179. JCI Insight. 2024. PMID: 38646933 Free article.
Generation of heterozygous PKD1 mutant pigs exhibiting early-onset renal cyst formation.
Watanabe M, Umeyama K, Nakano K, Matsunari H, Fukuda T, Matsumoto K, Tajiri S, Yamanaka S, Hasegawa K, Okamoto K, Uchikura A, Takayanagi S, Nagaya M, Yokoo T, Nakauchi H, Nagashima H. Watanabe M, et al. Among authors: umeyama k. Lab Invest. 2022 May;102(5):560-569. doi: 10.1038/s41374-021-00717-z. Epub 2022 Jan 3. Lab Invest. 2022. PMID: 34980882 Free PMC article.
Genetically engineered pigs manifesting pancreatic agenesis with severe diabetes.
Nagaya M, Hasegawa K, Watanabe M, Nakano K, Okamoto K, Yamada T, Uchikura A, Osafune K, Yokota H, Nagaoka T, Matsunari H, Umeyama K, Kobayashi E, Nakauchi H, Nagashima H. Nagaya M, et al. Among authors: umeyama k. BMJ Open Diabetes Res Care. 2020 Nov;8(2):e001792. doi: 10.1136/bmjdrc-2020-001792. BMJ Open Diabetes Res Care. 2020. PMID: 33257422 Free PMC article.
204 results