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Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs.
Illich DJ, Zhang M, Ursu A, Osorno R, Kim KP, Yoon J, Araúzo-Bravo MJ, Wu G, Esch D, Sabour D, Colby D, Grassme KS, Chen J, Greber B, Höing S, Herzog W, Ziegler S, Chambers I, Gao S, Waldmann H, Schöler HR. Illich DJ, et al. Among authors: ursu a. Cell Rep. 2016 Apr 26;15(4):787-800. doi: 10.1016/j.celrep.2016.03.073. Epub 2016 Apr 14. Cell Rep. 2016. PMID: 27149845 Free PMC article.
Small-molecule phenotypic screening with stem cells.
Ursu A, Schöler HR, Waldmann H. Ursu A, et al. Nat Chem Biol. 2017 May 17;13(6):560-563. doi: 10.1038/nchembio.2383. Nat Chem Biol. 2017. PMID: 28514421 No abstract available.
The Convergence of Stem Cell Technologies and Phenotypic Drug Discovery.
Friese A, Ursu A, Hochheimer A, Schöler HR, Waldmann H, Bruder JM. Friese A, et al. Among authors: ursu a. Cell Chem Biol. 2019 Aug 15;26(8):1050-1066. doi: 10.1016/j.chembiol.2019.05.007. Epub 2019 Jun 20. Cell Chem Biol. 2019. PMID: 31231030 Free article. Review.
Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß.
Kremer L, Hennes E, Brause A, Ursu A, Robke L, Matsubayashi HT, Nihongaki Y, Flegel J, Mejdrová I, Eickhoff J, Baumann M, Nencka R, Janning P, Kordes S, Schöler HR, Sterneckert J, Inoue T, Ziegler S, Waldmann H. Kremer L, et al. Among authors: ursu a. Angew Chem Int Ed Engl. 2019 Nov 11;58(46):16617-16628. doi: 10.1002/anie.201907632. Epub 2019 Oct 4. Angew Chem Int Ed Engl. 2019. PMID: 31454140 Free PMC article. Review.
Inducin Triggers LC3-Lipidation and ESCRT-Mediated Lysosomal Membrane Repair.
Corkery D, Ursu A, Lucas B, Grigalunas M, Kriegler S, Oliva R, Dec R, Koska S, Pahl A, Sievers S, Ziegler S, Winter R, Wu YW, Waldmann H. Corkery D, et al. Among authors: ursu a. Chembiochem. 2023 Dec 14;24(24):e202300579. doi: 10.1002/cbic.202300579. Epub 2023 Nov 7. Chembiochem. 2023. PMID: 37869939
The Hairpin Form of r(G4C2)exp in c9ALS/FTD Is Repeat-Associated Non-ATG Translated and a Target for Bioactive Small Molecules.
Wang ZF, Ursu A, Childs-Disney JL, Guertler R, Yang WY, Bernat V, Rzuczek SG, Fuerst R, Zhang YJ, Gendron TF, Yildirim I, Dwyer BG, Rice JE, Petrucelli L, Disney MD. Wang ZF, et al. Among authors: ursu a. Cell Chem Biol. 2019 Feb 21;26(2):179-190.e12. doi: 10.1016/j.chembiol.2018.10.018. Epub 2018 Nov 29. Cell Chem Biol. 2019. PMID: 30503283 Free PMC article.
49 results