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Did you mean verma cancer (5,191 results)?
KIAA1429/VIRMA promotes breast cancer progression by m(6) A-dependent cytosolic HAS2 stabilization.
Li N, Zhu Z, Deng Y, Tang R, Hui H, Kang Y, Rana TM. Li N, et al. EMBO Rep. 2023 Oct 9;24(10):e55506. doi: 10.15252/embr.202255506. Epub 2023 Sep 14. EMBO Rep. 2023. PMID: 37705505 Free PMC article.
KIAA1429/VIRMA is mislocalized to the cytosol of breast cancer tissues and cell lines, and shRNA-mediated knockdown inhibits breast cancer cell proliferation, migration, and invasion. ...HAS2 mRNA and KIAA1429/VIRMA mRNA levels correlate positively in …
KIAA1429/VIRMA is mislocalized to the cytosol of breast cancer tissues and cell lines, and shRNA-mediated knockdown inhibits b …
The potential role of RNA N6-methyladenosine in Cancer progression.
Wang T, Kong S, Tao M, Ju S. Wang T, et al. Mol Cancer. 2020 May 12;19(1):88. doi: 10.1186/s12943-020-01204-7. Mol Cancer. 2020. PMID: 32398132 Free PMC article. Review.
N6-methyladenosine (m6A) is considered the most common, abundant, and conserved internal transcript modification, especially in eukaryotic messenger RNA (mRNA). m6A is installed by m6A methyltransferases (METTL3/14, WTAP, RBM15/15B, VIRMA and ZC3H13, termed "writers"), rem …
N6-methyladenosine (m6A) is considered the most common, abundant, and conserved internal transcript modification, especially in eukaryotic m …
The role of m6A modification in the biological functions and diseases.
Jiang X, Liu B, Nie Z, Duan L, Xiong Q, Jin Z, Yang C, Chen Y. Jiang X, et al. Signal Transduct Target Ther. 2021 Feb 21;6(1):74. doi: 10.1038/s41392-020-00450-x. Signal Transduct Target Ther. 2021. PMID: 33611339 Free PMC article. Review.
N(6)-methyladenosine (m6A) is the most prevalent, abundant and conserved internal cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells. m6A modification is modified by the m6A methyltransferases, or writers, such as METTL3/14/16, RBM15/15B, …
N(6)-methyladenosine (m6A) is the most prevalent, abundant and conserved internal cotranscriptional modification in eukaryotic RNAs, especia …
VIRMA Facilitates Triple-Negative Breast Cancer Progression via Increasing m6A-Dependent KIF15 Expression.
Chen C, Wang Y, Li Y, Zhang C. Chen C, et al. Discov Med. 2023 Oct;35(178):787-795. doi: 10.24976/Discov.Med.202335178.73. Discov Med. 2023. PMID: 37811616
BACKGROUND: Vir like N6-methyladenosine (m6A) methyltransferase associated protein (VIRMA) is associated with various tumors, but the specific role of VIRMA in triple-negative breast cancer (TNBC) and the mechanisms are still unclear. Thus, in this study, in …
BACKGROUND: Vir like N6-methyladenosine (m6A) methyltransferase associated protein (VIRMA) is associated with various tumors, but the …
VIRMA contributes to non-small cell lung cancer progression via N(6)-methyladenosine-dependent DAPK3 post-transcriptional modification.
Xu Y, Chen Y, Yao Y, Xie H, Lu G, Du C, Cheng J, Zhou J. Xu Y, et al. Cancer Lett. 2021 Dec 1;522:142-154. doi: 10.1016/j.canlet.2021.08.027. Epub 2021 Sep 11. Cancer Lett. 2021. PMID: 34520821
VIRMA facilitated cell proliferation and tumor growth both in vitro and in vivo. ...Therefore, VIRMA may be a novel therapeutic target in NSCLC....
VIRMA facilitated cell proliferation and tumor growth both in vitro and in vivo. ...Therefore, VIRMA may be a novel therapeuti …
HNRNPC promotes collagen fiber alignment and immune evasion in breast cancer via activation of the VIRMA-mediated TFAP2A/DDR1 axis.
Lian B, Yan S, Li J, Bai Z, Li J. Lian B, et al. Mol Med. 2023 Aug 1;29(1):103. doi: 10.1186/s10020-023-00696-5. Mol Med. 2023. PMID: 37528369 Free PMC article.
BACKGROUND: Cancers aggressively reorganize collagen in their microenvironment, leading to the evasion of tumor cells from immune surveillance. ...In addition, HNRNPC promoted TFAP2A expression and, therefore, DDR1 transcription by recognizing the m6A modification of TFAP2 …
BACKGROUND: Cancers aggressively reorganize collagen in their microenvironment, leading to the evasion of tumor cells from immune sur …
The Cancer Genome Atlas (TCGA) based m(6)A methylation-related genes predict prognosis in hepatocellular carcinoma.
Liu J, Sun G, Pan S, Qin M, Ouyang R, Li Z, Huang J. Liu J, et al. Bioengineered. 2020 Dec;11(1):759-768. doi: 10.1080/21655979.2020.1787764. Bioengineered. 2020. PMID: 32631107 Free PMC article.
The current study aims to investigate the significance of N(6)-methyladenosine (m(6)A) methylation-related genes in the clinical prognosis of hepatocellular carcinoma (HCC) using bioinformatics analyses based on The Cancer Genome Atlas (TCGA) database. Transcriptome data a …
The current study aims to investigate the significance of N(6)-methyladenosine (m(6)A) methylation-related genes in the clinical prognosis o …
Role of m6A methyltransferase component VIRMA in multiple human cancers (Review).
Zhu W, Wang JZ, Wei JF, Lu C. Zhu W, et al. Cancer Cell Int. 2021 Mar 17;21(1):172. doi: 10.1186/s12935-021-01868-1. Cancer Cell Int. 2021. PMID: 33731118 Free PMC article. Review.
As a required component and the largest methyltransferase, vir-like m6A methyltransferase associated (VIRMA) can promote the progression of cancer and is associated with poor survival in multiple types of cancer. ...The obvious oncogenic roles of VIRMA …
As a required component and the largest methyltransferase, vir-like m6A methyltransferase associated (VIRMA) can promote the progress …
Overexpression of VIRMA confers vulnerability to breast cancers via the m(6)A-dependent regulation of unfolded protein response.
Lee Q, Song R, Phan DAV, Pinello N, Tieng J, Su A, Halstead JM, Wong ACH, van Geldermalsen M, Lee BS, Rong B, Cook KM, Larance M, Liu R, Lan F, Tiffen JC, Wong JJ. Lee Q, et al. Cell Mol Life Sci. 2023 May 19;80(6):157. doi: 10.1007/s00018-023-04799-4. Cell Mol Life Sci. 2023. PMID: 37208522 Free PMC article.
We show that VIRMA is amplified and overexpressed in 15-20% of breast cancers. ...Our study identifies oncogenic VIRMA overexpression as a vulnerability that may be exploited for cancer therapy....
We show that VIRMA is amplified and overexpressed in 15-20% of breast cancers. ...Our study identifies oncogenic VIRMA …
74 results