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Immune-awakening revealed by peripheral T cell dynamics after one cycle of immunotherapy.
Valpione S, Galvani E, Tweedy J, Mundra PA, Banyard A, Middlehurst P, Barry J, Mills S, Salih Z, Weightman J, Gupta A, Gremel G, Baenke F, Dhomen N, Lorigan PC, Marais R. Valpione S, et al. Nat Cancer. 2020 Feb;1(2):210-221. doi: 10.1038/s43018-019-0022-x. Epub 2020 Feb 10. Nat Cancer. 2020. PMID: 32110781 Free PMC article.
Sequential immunotherapy regimens-expect the unexpected.
Serra-Bellver P, Valpione S, Lorigan P. Serra-Bellver P, et al. Among authors: valpione s. Lancet Oncol. 2016 Jul;17(7):854-855. doi: 10.1016/S1470-2045(16)30198-X. Epub 2016 Jun 4. Lancet Oncol. 2016. PMID: 27269742 No abstract available.
Distinct subclonal tumour responses to therapy revealed by circulating cell-free DNA.
Gremel G, Lee RJ, Girotti MR, Mandal AK, Valpione S, Garner G, Ayub M, Wood S, Rothwell DG, Fusi A, Wallace A, Brady G, Dive C, Dhomen N, Lorigan P, Marais R. Gremel G, et al. Among authors: valpione s. Ann Oncol. 2016 Oct;27(10):1959-65. doi: 10.1093/annonc/mdw278. Epub 2016 Aug 8. Ann Oncol. 2016. PMID: 27502704 Free PMC article.
Rechallenge with BRAF-directed treatment in metastatic melanoma: A multi-institutional retrospective study.
Valpione S, Carlino MS, Mangana J, Mooradian MJ, McArthur G, Schadendorf D, Hauschild A, Menzies AM, Arance A, Ascierto PA, Di Giacomo A, de Rosa F, Larkin J, Park JJ, Goldinger SM, Sullivan RJ, Xu W, Livingstone E, Weichenthal M, Rai R, Gaba L, Long GV, Lorigan P. Valpione S, et al. Eur J Cancer. 2018 Mar;91:116-124. doi: 10.1016/j.ejca.2017.12.007. Epub 2018 Jan 19. Eur J Cancer. 2018. PMID: 29360604 Free article.
Corrigendum to "Rechallenge with BRAF-directed treatment in metastatic melanoma: A multi-institutional retrospective study*" [Eur J Cancer 91 (2018) 116-124].
Valpione S, Carlino MS, Mangana J, Mooradian MJ, McArthur G, Schadendorf D, Hauschild A, Menzies AM, Arance A, Ascierto PA, Giacomo AD, de Rosa F, Larkin J, Park JJ, Goldinger SM, Sullivan RJ, Xu W, Livingstone E, Weichenthal M, Rai R, Gaba L, Long GV, Lorigan P. Valpione S, et al. Eur J Cancer. 2018 Apr;93:158. doi: 10.1016/j.ejca.2018.02.001. Epub 2018 Mar 13. Eur J Cancer. 2018. PMID: 29548533 No abstract available.
Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma.
Galvani E, Mundra PA, Valpione S, Garcia-Martinez P, Smith M, Greenall J, Thakur R, Helmink B, Andrews MC, Boon L, Chester C, Gremel G, Hogan K, Mandal A, Zeng K, Banyard A, Ashton G, Cook M, Lorigan P, Wargo JA, Dhomen N, Marais R. Galvani E, et al. Among authors: valpione s. Nat Commun. 2020 Feb 12;11(1):853. doi: 10.1038/s41467-020-14632-2. Nat Commun. 2020. PMID: 32051401 Free PMC article.
Ultraviolet radiation drives mutations in a subset of mucosal melanomas.
Mundra PA, Dhomen N, Rodrigues M, Mikkelsen LH, Cassoux N, Brooks K, Valpione S, Reis-Filho JS, Heegaard S, Stern MH, Roman-Roman S, Marais R. Mundra PA, et al. Among authors: valpione s. Nat Commun. 2021 Jan 11;12(1):259. doi: 10.1038/s41467-020-20432-5. Nat Commun. 2021. PMID: 33431815 Free PMC article.
61 results