Thermodynamic benchmark study using Biacore technology.
Navratilova I, Papalia GA, Rich RL, Bedinger D, Brophy S, Condon B, Deng T, Emerick AW, Guan HW, Hayden T, Heutmekers T, Hoorelbeke B, McCroskey MC, Murphy MM, Nakagawa T, Parmeggiani F, Qin X, Rebe S, Tomasevic N, Tsang T, Waddell MB, Zhang FF, Leavitt S, Myszka DG.
Navratilova I, et al.
Anal Biochem. 2007 May 1;364(1):67-77. doi: 10.1016/j.ab.2007.01.031. Epub 2007 Jan 26.
Anal Biochem. 2007.
PMID: 17362870
Participants were provided with reagents (the enzyme carbonic anhydrase II, which was immobilized onto the sensor surface, and four sulfonamide-based inhibitors) and were instructed to collect response data from 6 to 36 degrees C. van't Hoff enthalpies and entropies were c …
Participants were provided with reagents (the enzyme carbonic anhydrase II, which was immobilized onto the sensor surface, and four sulfonam …