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Epithelial Indoleamine 2,3-Dioxygenase 1 Modulates Aryl Hydrocarbon Receptor and Notch Signaling to Increase Differentiation of Secretory Cells and Alter Mucus-Associated Microbiota.
Alvarado DM, Chen B, Iticovici M, Thaker AI, Dai N, VanDussen KL, Shaikh N, Lim CK, Guillemin GJ, Tarr PI, Ciorba MA. Alvarado DM, et al. Among authors: vandussen kl. Gastroenterology. 2019 Oct;157(4):1093-1108.e11. doi: 10.1053/j.gastro.2019.07.013. Epub 2019 Jul 17. Gastroenterology. 2019. PMID: 31325428 Free PMC article.
Abnormal Small Intestinal Epithelial Microvilli in Patients With Crohn's Disease.
VanDussen KL, Stojmirović A, Li K, Liu TC, Kimes PK, Muegge BD, Simpson KF, Ciorba MA, Perrigoue JG, Friedman JR, Towne JE, Head RD, Stappenbeck TS. VanDussen KL, et al. Gastroenterology. 2018 Sep;155(3):815-828. doi: 10.1053/j.gastro.2018.05.028. Epub 2018 May 18. Gastroenterology. 2018. PMID: 29782846 Free PMC article.
Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model.
Seiler KM, Bajinting A, Alvarado DM, Traore MA, Binkley MM, Goo WH, Lanik WE, Ou J, Ismail U, Iticovici M, King CR, VanDussen KL, Swietlicki EA, Gazit V, Guo J, Luke CJ, Stappenbeck T, Ciorba MA, George SC, Meacham JM, Rubin DC, Good M, Warner BW. Seiler KM, et al. Among authors: vandussen kl. Sci Rep. 2020 Mar 2;10(1):3842. doi: 10.1038/s41598-020-60672-5. Sci Rep. 2020. PMID: 32123209 Free PMC article.
Epithelial Cell Biomarkers Are Predictive of Response to Biologic Agents in Crohn's Disease.
Osterman MT, VanDussen KL, Gordon IO, Davis EM, Li K, Simpson K, Ciorba M, Glover SC, Abraham B, Guo X, Yee EU, Allard FD, Perrigoue JG, Claggett B, Shen B, Stappenbeck TS, Liu JJ. Osterman MT, et al. Among authors: vandussen kl. Inflamm Bowel Dis. 2021 Apr 15;27(5):677-685. doi: 10.1093/ibd/izaa251. Inflamm Bowel Dis. 2021. PMID: 32964238 Free PMC article. Clinical Trial.
ADAM10 regulates Notch function in intestinal stem cells of mice.
Tsai YH, VanDussen KL, Sawey ET, Wade AW, Kasper C, Rakshit S, Bhatt RG, Stoeck A, Maillard I, Crawford HC, Samuelson LC, Dempsey PJ. Tsai YH, et al. Among authors: vandussen kl. Gastroenterology. 2014 Oct;147(4):822-834.e13. doi: 10.1053/j.gastro.2014.07.003. Epub 2014 Jul 16. Gastroenterology. 2014. PMID: 25038433 Free PMC article.
PAI-1 augments mucosal damage in colitis.
Kaiko GE, Chen F, Lai CW, Chiang IL, Perrigoue J, Stojmirović A, Li K, Muegge BD, Jain U, VanDussen KL, Goggins BJ, Keely S, Weaver J, Foster PS, Lawrence DA, Liu TC, Stappenbeck TS. Kaiko GE, et al. Among authors: vandussen kl. Sci Transl Med. 2019 Mar 6;11(482):eaat0852. doi: 10.1126/scitranslmed.aat0852. Sci Transl Med. 2019. PMID: 30842312 Free PMC article.
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