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Lipid mixing between lipoplexes and plasma lipoproteins is a major barrier for intravenous transfection mediated by cationic lipids.
Tandia BM, Lonez C, Vandenbranden M, Ruysschaert JM, Elouahabi A. Tandia BM, et al. Among authors: vandenbranden m. J Biol Chem. 2005 Apr 1;280(13):12255-61. doi: 10.1074/jbc.M414517200. Epub 2005 Jan 20. J Biol Chem. 2005. PMID: 15661732 Free article.
It has been previously shown that transfection activity of cationic liposome/DNA lipoplexes delivered systemically is drastically inhibited by lipoproteins (Tandia, B. M., Vandenbranden, M., Wattiez, R., Lakhdar, Z., Ruysschaert, J. M., and Elouahabi, …
It has been previously shown that transfection activity of cationic liposome/DNA lipoplexes delivered systemically is drastically inhibited …
Cationic liposomal lipids: from gene carriers to cell signaling.
Lonez C, Vandenbranden M, Ruysschaert JM. Lonez C, et al. Among authors: vandenbranden m. Prog Lipid Res. 2008 Sep;47(5):340-7. doi: 10.1016/j.plipres.2008.03.002. Epub 2008 Apr 1. Prog Lipid Res. 2008. PMID: 18424270 Review.
Fusogenic activity of cationic lipids and lipid shape distribution.
Lonez C, Lensink MF, Kleiren E, Vanderwinden JM, Ruysschaert JM, Vandenbranden M. Lonez C, et al. Among authors: vandenbranden m. Cell Mol Life Sci. 2010 Feb;67(3):483-94. doi: 10.1007/s00018-009-0197-x. Epub 2009 Nov 19. Cell Mol Life Sci. 2010. PMID: 19924382
Cationic lipids activate intracellular signaling pathways.
Lonez C, Vandenbranden M, Ruysschaert JM. Lonez C, et al. Among authors: vandenbranden m. Adv Drug Deliv Rev. 2012 Dec;64(15):1749-58. doi: 10.1016/j.addr.2012.05.009. Epub 2012 May 23. Adv Drug Deliv Rev. 2012. PMID: 22634161 Review.
89 results