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Pyruvate dose response studies targeting the vital signs following hemorrhagic shock.
Sharma P, Vyacheslav M, Carissa C, Vanessa R, Bodo M. Sharma P, et al. J Emerg Trauma Shock. 2015 Jul-Sep;8(3):159-66. doi: 10.4103/0974-2700.160729. J Emerg Trauma Shock. 2015. PMID: 26229300 Free PMC article.
OBJECTIVES: To determine the optimal effective dose of sodium pyruvate in maintaining the vital signs following hemorrhagic shock (HS) in rats. MATERIALS AND METHODS: Anesthetized, male Sprague-Dawley rats underwent computer-controlled HS for 30 minute followed by fluid re …
OBJECTIVES: To determine the optimal effective dose of sodium pyruvate in maintaining the vital signs following hemorrhagic shock (HS) in ra …
Angiotensin-(1-7) improves oxygenation, while reducing cellular infiltrate and fibrosis in experimental Acute Respiratory Distress Syndrome.
Zambelli V, Bellani G, Borsa R, Pozzi F, Grassi A, Scanziani M, Castiglioni V, Masson S, Decio A, Laffey JG, Latini R, Pesenti A. Zambelli V, et al. Intensive Care Med Exp. 2015 Dec;3(1):44. doi: 10.1186/s40635-015-0044-3. Epub 2015 Feb 27. Intensive Care Med Exp. 2015. PMID: 26215809 Free PMC article.
This study was aimed at evaluating the potential for Ang-(1-7) to reduce injury, inflammation and fibrosis in an experimental model of ARDS in the acute and late phases. METHODS: Male Sprague Dawley rats underwent an instillation of 0.1 M hydrochloric acid (HCl, 2.5 ml/kg) …
This study was aimed at evaluating the potential for Ang-(1-7) to reduce injury, inflammation and fibrosis in an experimental model of ARDS …
The mGluR2 positive allosteric modulator, SAR218645, improves memory and attention deficits in translational models of cognitive symptoms associated with schizophrenia.
Griebel G, Pichat P, Boulay D, Naimoli V, Potestio L, Featherstone R, Sahni S, Defex H, Desvignes C, Slowinski F, Vigé X, Bergis OE, Sher R, Kosley R, Kongsamut S, Black MD, Varty GB. Griebel G, et al. Sci Rep. 2016 Oct 13;6:35320. doi: 10.1038/srep35320. Sci Rep. 2016. PMID: 27734956 Free PMC article.