Varani G - Search Results

1

A Small Cyclic β-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b.

Sun YT, Shortridge MD, Varani G. Sun YT, et al. Among authors: varani g. Chembiochem. 2019 Apr 1;20(7):931-939. doi: 10.1002/cbic.201800645. Epub 2019 Feb 15. Chembiochem. 2019. PMID: 30537200 Free PMC article.

2

Protein families and RNA recognition.

Chen Y, Varani G. Chen Y, et al. Among authors: varani g. FEBS J. 2005 May;272(9):2088-97. doi: 10.1111/j.1742-4658.2005.04650.x. FEBS J. 2005. PMID: 15853794 Free article. Review.

3

TAR RNA recognition by a cyclic peptidomimetic of Tat protein.

Leeper TC, Athanassiou Z, Dias RL, Robinson JA, Varani G. Leeper TC, et al. Among authors: varani g. Biochemistry. 2005 Sep 20;44(37):12362-72. doi: 10.1021/bi0510532. Biochemistry. 2005. PMID: 16156649

4

Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimics of Tat protein.

Davidson A, Leeper TC, Athanassiou Z, Patora-Komisarska K, Karn J, Robinson JA, Varani G. Davidson A, et al. Among authors: varani g. Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):11931-6. doi: 10.1073/pnas.0900629106. Epub 2009 Jul 7. Proc Natl Acad Sci U S A. 2009. PMID: 19584251 Free PMC article.

5

Essential structural requirements for specific recognition of HIV TAR RNA by peptide mimetics of Tat protein.

Davidson A, Patora-Komisarska K, Robinson JA, Varani G. Davidson A, et al. Among authors: varani g. Nucleic Acids Res. 2011 Jan;39(1):248-56. doi: 10.1093/nar/gkq713. Epub 2010 Aug 19. Nucleic Acids Res. 2011. PMID: 20724442 Free PMC article.

6

Structure based approaches for targeting non-coding RNAs with small molecules.

Shortridge MD, Varani G. Shortridge MD, et al. Among authors: varani g. Curr Opin Struct Biol. 2015 Feb;30:79-88. doi: 10.1016/j.sbi.2015.01.008. Epub 2015 Feb 16. Curr Opin Struct Biol. 2015. PMID: 25687935 Free PMC article. Review.

7

Targeted inhibition of oncogenic miR-21 maturation with designed RNA-binding proteins.

Chen Y, Yang F, Zubovic L, Pavelitz T, Yang W, Godin K, Walker M, Zheng S, Macchi P, Varani G. Chen Y, et al. Among authors: varani g. Nat Chem Biol. 2016 Sep;12(9):717-23. doi: 10.1038/nchembio.2128. Epub 2016 Jul 18. Nat Chem Biol. 2016. PMID: 27428511 Free PMC article.

8

Development of Small Molecules with a Noncanonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA.

Abulwerdi FA, Shortridge MD, Sztuba-Solinska J, Wilson R, Le Grice SF, Varani G, Schneekloth JS Jr. Abulwerdi FA, et al. Among authors: varani g. J Med Chem. 2016 Dec 22;59(24):11148-11160. doi: 10.1021/acs.jmedchem.6b01450. Epub 2016 Dec 2. J Med Chem. 2016. PMID: 28002966 Free PMC article.

9

A Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing.

Shortridge MD, Walker MJ, Pavelitz T, Chen Y, Yang W, Varani G. Shortridge MD, et al. Among authors: varani g. ACS Chem Biol. 2017 Jun 16;12(6):1611-1620. doi: 10.1021/acschembio.7b00180. Epub 2017 May 2. ACS Chem Biol. 2017. PMID: 28437065 Free PMC article.

10

Comprehensive computational design of ordered peptide macrocycles.

Hosseinzadeh P, Bhardwaj G, Mulligan VK, Shortridge MD, Craven TW, Pardo-Avila F, Rettie SA, Kim DE, Silva DA, Ibrahim YM, Webb IK, Cort JR, Adkins JN, Varani G, Baker D. Hosseinzadeh P, et al. Among authors: varani g. Science. 2017 Dec 15;358(6369):1461-1466. doi: 10.1126/science.aap7577. Science. 2017. PMID: 29242347 Free PMC article.

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