Vasudevan SG - Search Results

1

Mutagenesis of the dengue virus type 2 NS5 methyltransferase domain.

Kroschewski H, Lim SP, Butcher RE, Yap TL, Lescar J, Wright PJ, Vasudevan SG, Davidson AD. Kroschewski H, et al. Among authors: vasudevan sg. J Biol Chem. 2008 Jul 11;283(28):19410-21. doi: 10.1074/jbc.M800613200. Epub 2008 May 9. J Biol Chem. 2008. PMID: 18469001 Free article.

2

Flexibility between the protease and helicase domains of the dengue virus NS3 protein conferred by the linker region and its functional implications.

Luo D, Wei N, Doan DN, Paradkar PN, Chong Y, Davidson AD, Kotaka M, Lescar J, Vasudevan SG. Luo D, et al. Among authors: vasudevan sg. J Biol Chem. 2010 Jun 11;285(24):18817-27. doi: 10.1074/jbc.M109.090936. Epub 2010 Apr 7. J Biol Chem. 2010. PMID: 20375022 Free PMC article.

3

The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replication.

Tay MY, Saw WG, Zhao Y, Chan KW, Singh D, Chong Y, Forwood JK, Ooi EE, Grüber G, Lescar J, Luo D, Vasudevan SG. Tay MY, et al. Among authors: vasudevan sg. J Biol Chem. 2015 Jan 23;290(4):2379-94. doi: 10.1074/jbc.M114.607341. Epub 2014 Dec 8. J Biol Chem. 2015. PMID: 25488659 Free PMC article.

4

Structure-based mutational analysis of the NS3 helicase from dengue virus.

Sampath A, Xu T, Chao A, Luo D, Lescar J, Vasudevan SG. Sampath A, et al. Among authors: vasudevan sg. J Virol. 2006 Jul;80(13):6686-90. doi: 10.1128/JVI.02215-05. J Virol. 2006. PMID: 16775356 Free PMC article.

5

A multi-step strategy to obtain crystals of the dengue virus RNA-dependent RNA polymerase that diffract to high resolution.

Yap TL, Chen YL, Xu T, Wen D, Vasudevan SG, Lescar J. Yap TL, et al. Among authors: vasudevan sg. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Feb 1;63(Pt 2):78-83. doi: 10.1107/S1744309106055084. Epub 2007 Jan 17. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17277444 Free PMC article.

6

Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution.

Yap TL, Xu T, Chen YL, Malet H, Egloff MP, Canard B, Vasudevan SG, Lescar J. Yap TL, et al. Among authors: vasudevan sg. J Virol. 2007 May;81(9):4753-65. doi: 10.1128/JVI.02283-06. Epub 2007 Feb 14. J Virol. 2007. PMID: 17301146 Free PMC article.

7

Towards the design of flavivirus helicase/NTPase inhibitors: crystallographic and mutagenesis studies of the dengue virus NS3 helicase catalytic domain.

Xu T, Sampath A, Chao A, Wen D, Nanao M, Luo D, Chene P, Vasudevan SG, Lescar J. Xu T, et al. Among authors: vasudevan sg. Novartis Found Symp. 2006;277:87-97; discussion 97-101, 251-3. doi: 10.1002/0470058005.ch7. Novartis Found Symp. 2006. PMID: 17319156

8

Nuclear localization of dengue virus nonstructural protein 5 through its importin alpha/beta-recognized nuclear localization sequences is integral to viral infection.

Pryor MJ, Rawlinson SM, Butcher RE, Barton CL, Waterhouse TA, Vasudevan SG, Bardin PG, Wright PJ, Jans DA, Davidson AD. Pryor MJ, et al. Among authors: vasudevan sg. Traffic. 2007 Jul;8(7):795-807. doi: 10.1111/j.1600-0854.2007.00579.x. Epub 2007 May 30. Traffic. 2007. PMID: 17537211 Free article.

9

Crystal structure of the NS3 protease-helicase from dengue virus.

Luo D, Xu T, Hunke C, Grüber G, Vasudevan SG, Lescar J. Luo D, et al. Among authors: vasudevan sg. J Virol. 2008 Jan;82(1):173-83. doi: 10.1128/JVI.01788-07. Epub 2007 Oct 17. J Virol. 2008. PMID: 17942558 Free PMC article.

10

Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target.

Lescar J, Luo D, Xu T, Sampath A, Lim SP, Canard B, Vasudevan SG. Lescar J, et al. Among authors: vasudevan sg. Antiviral Res. 2008 Nov;80(2):94-101. doi: 10.1016/j.antiviral.2008.07.001. Epub 2008 Jul 30. Antiviral Res. 2008. PMID: 18674567 Review.

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