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Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression.
Van San E, Debruyne AC, Veeckmans G, Tyurina YY, Tyurin VA, Zheng H, Choi SM, Augustyns K, van Loo G, Michalke B, Venkataramani V, Toyokuni S, Bayir H, Vandenabeele P, Hassannia B, Vanden Berghe T. Van San E, et al. Among authors: venkataramani v. Cell Death Differ. 2023 Sep;30(9):2092-2103. doi: 10.1038/s41418-023-01195-0. Epub 2023 Aug 4. Cell Death Differ. 2023. PMID: 37542104 Free PMC article.
BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis.
Vara-Pérez M, Rossi M, Van den Haute C, Maes H, Sassano ML, Venkataramani V, Michalke B, Romano E, Rillaerts K, Garg AD, Schepkens C, Bosisio FM, Wouters J, Oliveira AI, Vangheluwe P, Annaert W, Swinnen JV, Colet JM, van den Oord JJ, Fendt SM, Mazzone M, Agostinis P. Vara-Pérez M, et al. Among authors: venkataramani v. EMBO J. 2021 May 17;40(10):e106214. doi: 10.15252/embj.2020106214. Epub 2021 May 1. EMBO J. 2021. PMID: 33932034 Free PMC article.
Manganese causes neurotoxic iron accumulation via translational repression of amyloid precursor protein and H-Ferritin.
Venkataramani V, Doeppner TR, Willkommen D, Cahill CM, Xin Y, Ye G, Liu Y, Southon A, Aron A, Au-Yeung HY, Huang X, Lahiri DK, Wang F, Bush AI, Wulf GG, Ströbel P, Michalke B, Rogers JT. Venkataramani V, et al. J Neurochem. 2018 Dec;147(6):831-848. doi: 10.1111/jnc.14580. Epub 2018 Nov 19. J Neurochem. 2018. PMID: 30152072 Free PMC article.
82 results