Verity N - Search Results

1

PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia.

Radford H, Moreno JA, Verity N, Halliday M, Mallucci GR. Radford H, et al. Among authors: verity n. Acta Neuropathol. 2015 Nov;130(5):633-42. doi: 10.1007/s00401-015-1487-z. Epub 2015 Oct 8. Acta Neuropathol. 2015. PMID: 26450683 Free PMC article.

2

Sustained translational repression by eIF2α-P mediates prion neurodegeneration.

Moreno JA, Radford H, Peretti D, Steinert JR, Verity N, Martin MG, Halliday M, Morgan J, Dinsdale D, Ortori CA, Barrett DA, Tsaytler P, Bertolotti A, Willis AE, Bushell M, Mallucci GR. Moreno JA, et al. Among authors: verity n. Nature. 2012 May 6;485(7399):507-11. doi: 10.1038/nature11058. Nature. 2012. PMID: 22622579 Free PMC article.

3

Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice.

Moreno JA, Halliday M, Molloy C, Radford H, Verity N, Axten JM, Ortori CA, Willis AE, Fischer PM, Barrett DA, Mallucci GR. Moreno JA, et al. Among authors: verity n. Sci Transl Med. 2013 Oct 9;5(206):206ra138. doi: 10.1126/scitranslmed.3006767. Sci Transl Med. 2013. PMID: 24107777

4

RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration.

Peretti D, Bastide A, Radford H, Verity N, Molloy C, Martin MG, Moreno JA, Steinert JR, Smith T, Dinsdale D, Willis AE, Mallucci GR. Peretti D, et al. Among authors: verity n. Nature. 2015 Feb 12;518(7538):236-9. doi: 10.1038/nature14142. Epub 2015 Jan 14. Nature. 2015. PMID: 25607368 Free PMC article.

5

Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice.

Halliday M, Radford H, Zents KAM, Molloy C, Moreno JA, Verity NC, Smith E, Ortori CA, Barrett DA, Bushell M, Mallucci GR. Halliday M, et al. Among authors: verity nc. Brain. 2017 Jun 1;140(6):1768-1783. doi: 10.1093/brain/awx074. Brain. 2017. PMID: 28430857 Free PMC article.

6

Targeting the kinase insert loop of PERK selectively modulates PERK signaling without systemic toxicity in mice.

Hughes DT, Halliday M, Smith HL, Verity NC, Molloy C, Radford H, Butcher AJ, Mallucci GR. Hughes DT, et al. Among authors: verity nc. Sci Signal. 2020 Aug 11;13(644):eabb4749. doi: 10.1126/scisignal.abb4749. Sci Signal. 2020. PMID: 32788341

7

Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity.

Halliday M, Radford H, Sekine Y, Moreno J, Verity N, le Quesne J, Ortori CA, Barrett DA, Fromont C, Fischer PM, Harding HP, Ron D, Mallucci GR. Halliday M, et al. Among authors: verity n. Cell Death Dis. 2015 Mar 5;6(3):e1672. doi: 10.1038/cddis.2015.49. Cell Death Dis. 2015. PMID: 25741597 Free PMC article.

8

TrkB signaling regulates the cold-shock protein RBM3-mediated neuroprotection.

Peretti D, Smith HL, Verity N, Humoud I, de Weerd L, Swinden DP, Hayes J, Mallucci GR. Peretti D, et al. Among authors: verity n. Life Sci Alliance. 2021 Feb 9;4(4):e202000884. doi: 10.26508/lsa.202000884. Print 2021 Apr. Life Sci Alliance. 2021. PMID: 33563652 Free PMC article.

9

Rescuing neurons in prion disease.

Verity NC, Mallucci GR. Verity NC, et al. Biochem J. 2011 Jan 1;433(1):19-29. doi: 10.1042/BJ20101323. Biochem J. 2011. PMID: 21158739 Review.

10

Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration.

Smith HL, Freeman OJ, Butcher AJ, Holmqvist S, Humoud I, Schätzl T, Hughes DT, Verity NC, Swinden DP, Hayes J, de Weerd L, Rowitch DH, Franklin RJM, Mallucci GR. Smith HL, et al. Among authors: verity nc. Neuron. 2020 Mar 4;105(5):855-866.e5. doi: 10.1016/j.neuron.2019.12.014. Epub 2020 Jan 7. Neuron. 2020. PMID: 31924446 Free PMC article.

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