Verkaar F - Search Results

1

Chemokine cooperativity is caused by competitive glycosaminoglycan binding.

Verkaar F, van Offenbeek J, van der Lee MMC, van Lith LHCJ, Watts AO, Rops ALWMM, Aguilar DC, Ziarek JJ, van der Vlag J, Handel TM, Volkman BF, Proudfoot AEI, Vischer HF, Zaman GJR, Smit MJ. Verkaar F, et al. J Immunol. 2014 Apr 15;192(8):3908-3914. doi: 10.4049/jimmunol.1302159. Epub 2014 Mar 17. J Immunol. 2014. PMID: 24639348 Free PMC article.

2

β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR.

Watts AO, Verkaar F, van der Lee MM, Timmerman CA, Kuijer M, van Offenbeek J, van Lith LH, Smit MJ, Leurs R, Zaman GJ, Vischer HF. Watts AO, et al. Among authors: verkaar f. J Biol Chem. 2013 Mar 8;288(10):7169-81. doi: 10.1074/jbc.M112.406108. Epub 2013 Jan 22. J Biol Chem. 2013. PMID: 23341447 Free PMC article.

3

A model for signaling specificity of Wnt/Frizzled combinations through co-receptor recruitment.

Verkaar F, Zaman GJ. Verkaar F, et al. FEBS Lett. 2010 Sep 24;584(18):3850-4. doi: 10.1016/j.febslet.2010.08.030. Epub 2010 Aug 25. FEBS Lett. 2010. PMID: 20800062 Free article.

4

β-Arrestin-biased signaling of PTH analogs of the type 1 parathyroid hormone receptor.

van der Lee MM, Verkaar F, Wat JW, van Offenbeek J, Timmerman M, Voorneveld L, van Lith LH, Zaman GJ. van der Lee MM, et al. Among authors: verkaar f. Cell Signal. 2013 Feb;25(2):527-38. doi: 10.1016/j.cellsig.2012.11.012. Epub 2012 Nov 15. Cell Signal. 2013. PMID: 23159578

5

New avenues to target Wnt/β-catenin signaling.

Verkaar F, Zaman GJ. Verkaar F, et al. Drug Discov Today. 2011 Jan;16(1-2):35-41. doi: 10.1016/j.drudis.2010.11.007. Epub 2010 Nov 24. Drug Discov Today. 2011. PMID: 21111060 Review.

6

Discovery of novel small molecule activators of β-catenin signaling.

Verkaar F, van der Stelt M, Blankesteijn WM, van der Doelen AA, Zaman GJ. Verkaar F, et al. PLoS One. 2011 Apr 29;6(4):e19185. doi: 10.1371/journal.pone.0019185. PLoS One. 2011. PMID: 21559429 Free PMC article.

7

Constitutive β-catenin signaling by the viral chemokine receptor US28.

Langemeijer EV, Slinger E, de Munnik S, Schreiber A, Maussang D, Vischer H, Verkaar F, Leurs R, Siderius M, Smit MJ. Langemeijer EV, et al. Among authors: verkaar f. PLoS One. 2012;7(11):e48935. doi: 10.1371/journal.pone.0048935. Epub 2012 Nov 8. PLoS One. 2012. PMID: 23145028 Free PMC article.

8

A prospective cross-screening study on G-protein-coupled receptors: lessons learned in virtual compound library design.

Sanders MP, Roumen L, van der Horst E, Lane JR, Vischer HF, van Offenbeek J, de Vries H, Verhoeven S, Chow KY, Verkaar F, Beukers MW, McGuire R, Leurs R, Ijzerman AP, de Vlieg J, de Esch IJ, Zaman GJ, Klomp JP, Bender A, de Graaf C. Sanders MP, et al. Among authors: verkaar f. J Med Chem. 2012 Jun 14;55(11):5311-25. doi: 10.1021/jm300280e. Epub 2012 May 23. J Med Chem. 2012. PMID: 22563707

9

G protein-independent cell-based assays for drug discovery on seven-transmembrane receptors.

Verkaar F, van Rosmalen JW, Blomenröhr M, van Koppen CJ, Blankesteijn WM, Smits JF, Zaman GJ. Verkaar F, et al. Biotechnol Annu Rev. 2008;14:253-74. doi: 10.1016/S1387-2656(08)00010-0. Biotechnol Annu Rev. 2008. PMID: 18606367 Review.

10

Stably overexpressed human Frizzled-2 signals through the beta-catenin pathway and does not activate Ca2+-mobilization in Human Embryonic Kidney 293 cells.

Verkaar F, van Rosmalen JW, Smits JF, Blankesteijn WM, Zaman GJ. Verkaar F, et al. Cell Signal. 2009 Jan;21(1):22-33. doi: 10.1016/j.cellsig.2008.09.008. Epub 2008 Sep 25. Cell Signal. 2009. PMID: 18929644

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