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CFTR inhibitors for treating diarrheal disease.
Thiagarajah JR, Verkman AS. Thiagarajah JR, et al. Among authors: verkman as. Clin Pharmacol Ther. 2012 Sep;92(3):287-90. doi: 10.1038/clpt.2012.114. Epub 2012 Aug 1. Clin Pharmacol Ther. 2012. PMID: 22850599 Free PMC article. Review.
A multifunctional aqueous channel formed by CFTR.
Hasegawa H, Skach W, Baker O, Calayag MC, Lingappa V, Verkman AS. Hasegawa H, et al. Among authors: verkman as. Science. 1992 Nov 27;258(5087):1477-9. doi: 10.1126/science.1279809. Science. 1992. PMID: 1279809
Functional CFTR in endosomal compartment of CFTR-expressing fibroblasts and T84 cells.
Biwersi J, Verkman AS. Biwersi J, et al. Among authors: verkman as. Am J Physiol. 1994 Jan;266(1 Pt 1):C149-56. doi: 10.1152/ajpcell.1994.266.1.C149. Am J Physiol. 1994. PMID: 7508186
It was proposed that the cystic fibrosis transmembrane conductance regulator (CFTR) functions in the endosomal compartment as a adenosine 3',5'-cyclic monophosphate (cAMP)-regulated Cl channel that regulates endosomal acidification (J. ...In fibroblasts, the time course of …
It was proposed that the cystic fibrosis transmembrane conductance regulator (CFTR) functions in the endosomal compartment as a adeno …
Evidence against defective trans-Golgi acidification in cystic fibrosis.
Seksek O, Biwersi J, Verkman AS. Seksek O, et al. Among authors: verkman as. J Biol Chem. 1996 Jun 28;271(26):15542-8. doi: 10.1074/jbc.271.26.15542. J Biol Chem. 1996. PMID: 8663158 Free article.
Defective organelle acidification has been proposed as a unifying hypothesis to explain the pleiotropic cellular abnormalities associated with cystic fibrosis. To test whether cystic fibrosis transmembrane conductance regulator (CFTR) participates in trans-Golgi pH regulat …
Defective organelle acidification has been proposed as a unifying hypothesis to explain the pleiotropic cellular abnormalities associ …
699 results