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Using genomics to study how chromatin influences gene expression.
Higgs DR, Vernimmen D, Hughes J, Gibbons R. Higgs DR, et al. Among authors: vernimmen d. Annu Rev Genomics Hum Genet. 2007;8:299-325. doi: 10.1146/annurev.genom.8.080706.092323. Annu Rev Genomics Hum Genet. 2007. PMID: 17506662 Review.
Adventitious changes in long-range gene expression caused by polymorphic structural variation and promoter competition.
Lower KM, Hughes JR, De Gobbi M, Henderson S, Viprakasit V, Fisher C, Goriely A, Ayyub H, Sloane-Stanley J, Vernimmen D, Langford C, Garrick D, Gibbons RJ, Higgs DR. Lower KM, et al. Among authors: vernimmen d. Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21771-6. doi: 10.1073/pnas.0909331106. Epub 2009 Dec 3. Proc Natl Acad Sci U S A. 2009. PMID: 19959666 Free PMC article.
High-resolution analysis of cis-acting regulatory networks at the α-globin locus.
Hughes JR, Lower KM, Dunham I, Taylor S, De Gobbi M, Sloane-Stanley JA, McGowan S, Ragoussis J, Vernimmen D, Gibbons RJ, Higgs DR. Hughes JR, et al. Among authors: vernimmen d. Philos Trans R Soc Lond B Biol Sci. 2013 May 6;368(1620):20120361. doi: 10.1098/rstb.2012.0361. Print 2013. Philos Trans R Soc Lond B Biol Sci. 2013. PMID: 23650635 Free PMC article.
33 results