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A mutation in calsequestrin, CASQ2D307H, impairs Sarcoplasmic Reticulum Ca2+ handling and causes complex ventricular arrhythmias in mice.
Dirksen WP, Lacombe VA, Chi M, Kalyanasundaram A, Viatchenko-Karpinski S, Terentyev D, Zhou Z, Vedamoorthyrao S, Li N, Chiamvimonvat N, Carnes CA, Franzini-Armstrong C, Györke S, Periasamy M. Dirksen WP, et al. Cardiovasc Res. 2007 Jul 1;75(1):69-78. doi: 10.1016/j.cardiores.2007.03.002. Epub 2007 Mar 12. Cardiovasc Res. 2007. PMID: 17449018 Free PMC article.
Diesterified nitrone rescues nitroso-redox levels and increases myocyte contraction via increased SR Ca(2+) handling.
Traynham CJ, Roof SR, Wang H, Prosak RA, Tang L, Viatchenko-Karpinski S, Ho HT, Racoma IO, Catalano DJ, Huang X, Han Y, Kim SU, Gyorke S, Billman GE, Villamena FA, Ziolo MT. Traynham CJ, et al. Among authors: viatchenko karpinski s. PLoS One. 2012;7(12):e52005. doi: 10.1371/journal.pone.0052005. Epub 2012 Dec 27. PLoS One. 2012. PMID: 23300588 Free PMC article.
Functional consequences of stably expressing a mutant calsequestrin (CASQ2D307H) in the CASQ2 null background.
Kalyanasundaram A, Viatchenko-Karpinski S, Belevych AE, Lacombe VA, Hwang HS, Knollmann BC, Gyorke S, Periasamy M. Kalyanasundaram A, et al. Among authors: viatchenko karpinski s. Am J Physiol Heart Circ Physiol. 2012 Jan 1;302(1):H253-61. doi: 10.1152/ajpheart.00578.2011. Epub 2011 Oct 7. Am J Physiol Heart Circ Physiol. 2012. PMID: 21984545 Free PMC article.
Abnormal intrastore calcium signaling in chronic heart failure.
Kubalova Z, Terentyev D, Viatchenko-Karpinski S, Nishijima Y, Györke I, Terentyeva R, da Cuñha DN, Sridhar A, Feldman DS, Hamlin RL, Carnes CA, Györke S. Kubalova Z, et al. Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):14104-9. doi: 10.1073/pnas.0504298102. Epub 2005 Sep 19. Proc Natl Acad Sci U S A. 2005. PMID: 16172392 Free PMC article.
Abnormal interactions of calsequestrin with the ryanodine receptor calcium release channel complex linked to exercise-induced sudden cardiac death.
Terentyev D, Nori A, Santoro M, Viatchenko-Karpinski S, Kubalova Z, Gyorke I, Terentyeva R, Vedamoorthyrao S, Blom NA, Valle G, Napolitano C, Williams SC, Volpe P, Priori SG, Gyorke S. Terentyev D, et al. Circ Res. 2006 May 12;98(9):1151-8. doi: 10.1161/01.RES.0000220647.93982.08. Epub 2006 Apr 6. Circ Res. 2006. PMID: 16601229
36 results