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Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.
Rodríguez-Nuevo A, Díaz-Ramos A, Noguera E, Díaz-Sáez F, Duran X, Muñoz JP, Romero M, Plana N, Sebastián D, Tezze C, Romanello V, Ribas F, Seco J, Planet E, Doctrow SR, González J, Borràs M, Liesa M, Palacín M, Vendrell J, Villarroya F, Sandri M, Shirihai O, Zorzano A. Rodríguez-Nuevo A, et al. Among authors: villarroya f. EMBO J. 2018 May 15;37(10):e96553. doi: 10.15252/embj.201796553. Epub 2018 Apr 9. EMBO J. 2018. PMID: 29632021 Free PMC article.
Peroxisome proliferator-activated receptor-gamma coactivator-1alpha controls transcription of the Sirt3 gene, an essential component of the thermogenic brown adipocyte phenotype.
Giralt A, Hondares E, Villena JA, Ribas F, Díaz-Delfín J, Giralt M, Iglesias R, Villarroya F. Giralt A, et al. Among authors: villarroya f. J Biol Chem. 2011 May 13;286(19):16958-66. doi: 10.1074/jbc.M110.202390. Epub 2011 Mar 27. J Biol Chem. 2011. PMID: 21454513 Free PMC article.
FGF21 mediates the lipid metabolism response to amino acid starvation.
De Sousa-Coelho AL, Relat J, Hondares E, Pérez-Martí A, Ribas F, Villarroya F, Marrero PF, Haro D. De Sousa-Coelho AL, et al. Among authors: villarroya f. J Lipid Res. 2013 Jul;54(7):1786-97. doi: 10.1194/jlr.M033415. Epub 2013 May 9. J Lipid Res. 2013. PMID: 23661803 Free PMC article.
Fibroblast growth factor 21 protects the heart from oxidative stress.
Planavila A, Redondo-Angulo I, Ribas F, Garrabou G, Casademont J, Giralt M, Villarroya F. Planavila A, et al. Among authors: villarroya f. Cardiovasc Res. 2015 Apr 1;106(1):19-31. doi: 10.1093/cvr/cvu263. Epub 2014 Dec 23. Cardiovasc Res. 2015. PMID: 25538153
Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation.
Malandrino MI, Fucho R, Weber M, Calderon-Dominguez M, Mir JF, Valcarcel L, Escoté X, Gómez-Serrano M, Peral B, Salvadó L, Fernández-Veledo S, Casals N, Vázquez-Carrera M, Villarroya F, Vendrell JJ, Serra D, Herrero L. Malandrino MI, et al. Among authors: villarroya f. Am J Physiol Endocrinol Metab. 2015 May 1;308(9):E756-69. doi: 10.1152/ajpendo.00362.2014. Epub 2015 Feb 24. Am J Physiol Endocrinol Metab. 2015. PMID: 25714670 Free article.
Lactate induces FGF21 expression in adipocytes through a p38-MAPK pathway.
Jeanson Y, Ribas F, Galinier A, Arnaud E, Ducos M, André M, Chenouard V, Villarroya F, Casteilla L, Carrière A. Jeanson Y, et al. Among authors: villarroya f. Biochem J. 2016 Mar 15;473(6):685-92. doi: 10.1042/BJ20150808. Epub 2016 Jan 14. Biochem J. 2016. PMID: 26769382
Nicotinamide Protects Against Diet-Induced Body Weight Gain, Increases Energy Expenditure, and Induces White Adipose Tissue Beiging.
Méndez-Lara KA, Rodríguez-Millán E, Sebastián D, Blanco-Soto R, Camacho M, Nan MN, Diarte-Añazco EMG, Mato E, Lope-Piedrafita S, Roglans N, Laguna JC, Alonso N, Mauricio D, Zorzano A, Villarroya F, Villena JA, Blanco-Vaca F, Julve J. Méndez-Lara KA, et al. Among authors: villarroya f. Mol Nutr Food Res. 2021 Jun;65(11):e2100111. doi: 10.1002/mnfr.202100111. Epub 2021 May 5. Mol Nutr Food Res. 2021. PMID: 33870623
Mfn2 localization in the ER is necessary for its bioenergetic function and neuritic development.
Casellas-Díaz S, Larramona-Arcas R, Riqué-Pujol G, Tena-Morraja P, Müller-Sánchez C, Segarra-Mondejar M, Gavaldà-Navarro A, Villarroya F, Reina M, Martínez-Estrada OM, Soriano FX. Casellas-Díaz S, et al. Among authors: villarroya f. EMBO Rep. 2021 Sep 6;22(9):e51954. doi: 10.15252/embr.202051954. Epub 2021 Jul 23. EMBO Rep. 2021. PMID: 34296790 Free PMC article.
312 results