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35 results

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Page 1
Cholangiocarcinoma.
Brindley PJ, Bachini M, Ilyas SI, Khan SA, Loukas A, Sirica AE, Teh BT, Wongkham S, Gores GJ. Brindley PJ, et al. Nat Rev Dis Primers. 2021 Sep 9;7(1):65. doi: 10.1038/s41572-021-00300-2. Nat Rev Dis Primers. 2021. PMID: 34504109 Free PMC article. Review.
In other regions, CCA can be associated with chronic biliary tract inflammation owing to choledocholithiasis, cholelithiasis, or primary sclerosing cholangitis, but most CCAs have no identifiable cause. ...
In other regions, CCA can be associated with chronic biliary tract inflammation owing to choledocholithiasis, cholelithiasis, or primary …
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.
Ji SG, Juran BD, Mucha S, Folseraas T, Jostins L, Melum E, Kumasaka N, Atkinson EJ, Schlicht EM, Liu JZ, Shah T, Gutierrez-Achury J, Boberg KM, Bergquist A, Vermeire S, Eksteen B, Durie PR, Farkkila M, Müller T, Schramm C, Sterneck M, Weismüller TJ, Gotthardt DN, Ellinghaus D, Braun F, Teufel A, Laudes M, Lieb W, Jacobs G, Beuers U, Weersma RK, Wijmenga C, Marschall HU, Milkiewicz P, Pares A, Kontula K, Chazouillères O, Invernizzi P, Goode E, Spiess K, Moore C, Sambrook J, Ouwehand WH, Roberts DJ, Danesh J, Floreani A, Gulamhusein AF, Eaton JE, Schreiber S, Coltescu C, Bowlus CL, Luketic VA, Odin JA, Chopra KB, Kowdley KV, Chalasani N, Manns MP, Srivastava B, Mells G, Sandford RN, Alexander G, Gaffney DJ, Chapman RW, Hirschfield GM, de Andrade M; UK-PSC Consortium; International IBD Genetics Consortium; International PSC Study Group; Rushbrook SM, Franke A, Karlsen TH, Lazaridis KN, Anderson CA. Ji SG, et al. Nat Genet. 2017 Feb;49(2):269-273. doi: 10.1038/ng.3745. Epub 2016 Dec 19. Nat Genet. 2017. PMID: 27992413 Free PMC article.
Primary sclerosing cholangitis (PSC) is a rare progressive disorder leading to bile duct destruction; 75% of patients have comorbid inflammatory bowel disease (IBD). ...
Primary sclerosing cholangitis (PSC) is a rare progressive disorder leading to bile duct destruction; 75% of patients h …
Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC.
Awoniyi M, Wang J, Ngo B, Meadows V, Tam J, Viswanathan A, Lai Y, Montgomery S, Farmer M, Kummen M, Thingholm L, Schramm C, Bang C, Franke A, Lu K, Zhou H, Bajaj JS, Hylemon PB, Ting J, Popov YV, Hov JR, Francis HL, Sartor RB. Awoniyi M, et al. Gut. 2023 Apr;72(4):671-685. doi: 10.1136/gutjnl-2021-326500. Epub 2022 Jun 15. Gut. 2023. PMID: 35705368 Free PMC article.
OBJECTIVE: Conflicting microbiota data exist for primary sclerosing cholangitis (PSC) and experimental models. GOAL: define the function of complex resident microbes and their association relevant to PSC patients by studying germ-free (GF) and antibiotic-trea …
OBJECTIVE: Conflicting microbiota data exist for primary sclerosing cholangitis (PSC) and experimental models. GOAL: de …
Secondary sclerosing cholangitis: mimics of primary sclerosing cholangitis.
Ludwig DR, Anderson MA, Itani M, Sharbidre KG, Lalwani N, Paspulati RM. Ludwig DR, et al. Abdom Radiol (NY). 2023 Jan;48(1):151-165. doi: 10.1007/s00261-022-03551-z. Epub 2022 May 18. Abdom Radiol (NY). 2023. PMID: 35585354 Free PMC article. Review.
Sclerosing cholangitis is a chronic cholestatic disease characterized by stricturing, beading, and obliterative fibrosis of the bile ducts. Sclerosing cholangitis is considered primary (PSC) if no underlying etiology is identified or secondary ( …
Sclerosing cholangitis is a chronic cholestatic disease characterized by stricturing, beading, and obliterative fibrosis of th …
Bile Acids and Biliary Fibrosis.
Aseem SO, Hylemon PB, Zhou H. Aseem SO, et al. Cells. 2023 Mar 2;12(5):792. doi: 10.3390/cells12050792. Cells. 2023. PMID: 36899928 Free PMC article. Review.
Biliary fibrosis is the driving pathological process in cholangiopathies such as primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). ...
Biliary fibrosis is the driving pathological process in cholangiopathies such as primary biliary cholangitis (PBC) and prim …
Cholangiocyte-Derived Exosomal Long Noncoding RNA H19 Promotes Hepatic Stellate Cell Activation and Cholestatic Liver Fibrosis.
Liu R, Li X, Zhu W, Wang Y, Zhao D, Wang X, Gurley EC, Liang G, Chen W, Lai G, Pandak WM, Robert Lippman H, Bajaj JS, Hylemon PB, Zhou H. Liu R, et al. Hepatology. 2019 Oct;70(4):1317-1335. doi: 10.1002/hep.30662. Epub 2019 May 24. Hepatology. 2019. PMID: 30985008 Free PMC article.
Activation of hepatic stellate cells (HSCs) represents the primary driving force to promote the progression of chronic cholestatic liver diseases. ...Collagen gel contraction and bromodeoxyuridine assays were used to determine the effect of exosomal-H19 on HSC activation a …
Activation of hepatic stellate cells (HSCs) represents the primary driving force to promote the progression of chronic cholestatic li …
Bile acid-mediated signaling in cholestatic liver diseases.
Zeng J, Fan J, Zhou H. Zeng J, et al. Cell Biosci. 2023 Apr 29;13(1):77. doi: 10.1186/s13578-023-01035-1. Cell Biosci. 2023. PMID: 37120573 Free PMC article. Review.
Chronic cholestatic liver diseases, such as primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), are associated with bile stasis and gradually progress to fibrosis, cirrhosis, and liver failure, which requires liver transp …
Chronic cholestatic liver diseases, such as primary biliary cholangitis (PBC) and primary sclerosing cholangi …
Gut Microbiome and Alcohol-associated Liver Disease.
Philips CA, Schnabl B, Bajaj JS. Philips CA, et al. J Clin Exp Hepatol. 2022 Sep-Oct;12(5):1349-1359. doi: 10.1016/j.jceh.2021.12.016. Epub 2022 Jan 4. J Clin Exp Hepatol. 2022. PMID: 36157139 Free PMC article. Review.
Changes in gut microbiota (GM) may be associated with the causation and progression of multiple liver diseases such as metabolic-associated liver disease, alcohol-associated liver disease (ALD), alcohol-associated hepatitis (AH), primary biliary cholangitis, prim …
Changes in gut microbiota (GM) may be associated with the causation and progression of multiple liver diseases such as metabolic-associated …
Protein and miRNA profile of circulating extracellular vesicles in patients with primary sclerosing cholangitis.
Povero D, Tameda M, Eguchi A, Ren W, Kim J, Myers R, Goodman ZD, Harrison SA, Sanyal AJ, Bosch J, Ohno-Machado L, Feldstein AE. Povero D, et al. Sci Rep. 2022 Feb 22;12(1):3027. doi: 10.1038/s41598-022-06809-0. Sci Rep. 2022. PMID: 35194091 Free PMC article.
Primary sclerosing cholangitis (PSC) is an idiopathic and heterogenous cholestatic liver disease characterized by chronic inflammation and fibrosis of the biliary tree. ...
Primary sclerosing cholangitis (PSC) is an idiopathic and heterogenous cholestatic liver disease characterized by chron …
Reporting standards for primary sclerosing cholangitis using MRI and MR cholangiopancreatography: guidelines from MR Working Group of the International Primary Sclerosing Cholangitis Study Group.
Venkatesh SK, Welle CL, Miller FH, Jhaveri K, Ringe KI, Eaton JE, Bungay H, Arrivé L, Ba-Ssalamah A, Grigoriadis A, Schramm C, Fulcher AS; IPSCSG. Venkatesh SK, et al. Eur Radiol. 2022 Feb;32(2):923-937. doi: 10.1007/s00330-021-08147-7. Epub 2021 Aug 6. Eur Radiol. 2022. PMID: 34363134
Primary sclerosing cholangitis (PSC) is a chronic inflammatory disorder affecting the bile ducts and is characterized by biliary strictures, progressive liver parenchymal fibrosis, and an increased risk of hepatobiliary malignancies primarily cholangiocarcino …
Primary sclerosing cholangitis (PSC) is a chronic inflammatory disorder affecting the bile ducts and is characterized b …
35 results