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The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma.
Gravina GL, Mancini A, Marampon F, Colapietro A, Delle Monache S, Sferra R, Vitale F, Richardson PJ, Patient L, Burbidge S, Festuccia C. Gravina GL, et al. Among authors: vitale f. J Hematol Oncol. 2017 Jan 5;10(1):5. doi: 10.1186/s13045-016-0377-8. J Hematol Oncol. 2017. PMID: 28057017 Free PMC article.
The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models.
Gravina GL, Mancini A, Colapietro A, Vitale F, Vetuschi A, Pompili S, Rossi G, Marampon F, Richardson PJ, Patient L, Patient L, Burbidge S, Festuccia C. Gravina GL, et al. Among authors: vitale f. Tumour Biol. 2017 Jun;39(6):1010428317695528. doi: 10.1177/1010428317695528. Tumour Biol. 2017. PMID: 28639900 Free article.
The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma.
Festuccia C, Mancini A, Colapietro A, Gravina GL, Vitale F, Marampon F, Delle Monache S, Pompili S, Cristiano L, Vetuschi A, Tombolini V, Chen Y, Mehrling T. Festuccia C, et al. Among authors: vitale f. J Hematol Oncol. 2018 Feb 27;11(1):32. doi: 10.1186/s13045-018-0576-6. J Hematol Oncol. 2018. PMID: 29486795 Free PMC article.
The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models.
Gravina GL, Mancini A, Colapietro A, Delle Monache S, Sferra R, Vitale F, Cristiano L, Martellucci S, Marampon F, Mattei V, Beirinckx F, Pujuguet P, Saniere L, Lorenzon G, van der Aar E, Festuccia C. Gravina GL, et al. Among authors: vitale f. Cancers (Basel). 2019 Mar 13;11(3):359. doi: 10.3390/cancers11030359. Cancers (Basel). 2019. PMID: 30871240 Free PMC article.
The Brain Penetrating and Dual TORC1/TORC2 Inhibitor, RES529, Elicits Anti-Glioma Activity and Enhances the Therapeutic Effects of Anti-Angiogenetic Compounds in Preclinical Murine Models.
Gravina GL, Mancini A, Colapietro A, Delle Monache S, Sferra R, Pompili S, Vitale F, Martellucci S, Marampon F, Mattei V, Biordi L, Sherris D, Festuccia C. Gravina GL, et al. Among authors: vitale f. Cancers (Basel). 2019 Oct 21;11(10):1604. doi: 10.3390/cancers11101604. Cancers (Basel). 2019. PMID: 31640252 Free PMC article.
The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, Inhibits Growth of Human Glioblastoma, Reduces Akt/mTOR Activities, and Modulates GSC Cell-Renewal Properties.
Colapietro A, Yang P, Rossetti A, Mancini A, Vitale F, Martellucci S, Conway TL, Chakraborty S, Marampon F, Mattei V, Gravina GL, Biordi AL, Wei D, Newman RA, Festuccia C. Colapietro A, et al. Among authors: vitale f. Front Pharmacol. 2020 Sep 11;11:552428. doi: 10.3389/fphar.2020.552428. eCollection 2020. Front Pharmacol. 2020. PMID: 33013390 Free PMC article.
The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, Is Synergistic With Radiotherapy in Models of Human Glioblastoma.
Colapietro A, Yang P, Rossetti A, Mancini A, Vitale F, Chakraborty S, Martellucci S, Marampon F, Mattei V, Gravina GL, Iorio R, Newman RA, Festuccia C. Colapietro A, et al. Among authors: vitale f. Front Pharmacol. 2022 Mar 23;13:852941. doi: 10.3389/fphar.2022.852941. eCollection 2022. Front Pharmacol. 2022. PMID: 35401175 Free PMC article.
607 results