Vlaming ML - Search Results

1

Hepatic transport mechanisms of cholyl-L-lysyl-fluorescein.

de Waart DR, Häusler S, Vlaming ML, Kunne C, Hänggi E, Gruss HJ, Oude Elferink RP, Stieger B. de Waart DR, et al. Among authors: vlaming ml. J Pharmacol Exp Ther. 2010 Jul;334(1):78-86. doi: 10.1124/jpet.110.166991. Epub 2010 Apr 13. J Pharmacol Exp Ther. 2010. PMID: 20388726

2

Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2.

de Waart DR, Vlaming ML, Kunne C, Schinkel AH, Oude Elferink RP. de Waart DR, et al. Among authors: vlaming ml. Drug Metab Dispos. 2009 Aug;37(8):1698-702. doi: 10.1124/dmd.108.026146. Epub 2009 May 14. Drug Metab Dispos. 2009. PMID: 19443695

3

Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice.

Vlaming ML, Mohrmann K, Wagenaar E, de Waart DR, Elferink RP, Lagas JS, van Tellingen O, Vainchtein LD, Rosing H, Beijnen JH, Schellens JH, Schinkel AH. Vlaming ML, et al. J Pharmacol Exp Ther. 2006 Jul;318(1):319-27. doi: 10.1124/jpet.106.101774. Epub 2006 Apr 12. J Pharmacol Exp Ther. 2006. PMID: 16611851 Free article.

4

Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.

Vlaming ML, Pala Z, van Esch A, Wagenaar E, van Tellingen O, de Waart DR, Oude Elferink RP, van de Wetering K, Schinkel AH. Vlaming ML, et al. Clin Cancer Res. 2008 Dec 15;14(24):8152-60. doi: 10.1158/1078-0432.CCR-08-1609. Clin Cancer Res. 2008. PMID: 19088030

5

Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo.

Vlaming ML, Pala Z, van Esch A, Wagenaar E, de Waart DR, van de Wetering K, van der Kruijssen CM, Oude Elferink RP, van Tellingen O, Schinkel AH. Vlaming ML, et al. Clin Cancer Res. 2009 May 1;15(9):3084-93. doi: 10.1158/1078-0432.CCR-08-2940. Epub 2009 Apr 21. Clin Cancer Res. 2009. PMID: 19383815

6

Multidrug resistance proteins 2 and 3 provide alternative routes for hepatic excretion of morphine-glucuronides.

van de Wetering K, Zelcer N, Kuil A, Feddema W, Hillebrand M, Vlaming ML, Schinkel AH, Beijnen JH, Borst P. van de Wetering K, et al. Among authors: vlaming ml. Mol Pharmacol. 2007 Aug;72(2):387-94. doi: 10.1124/mol.107.035592. Epub 2007 May 7. Mol Pharmacol. 2007. PMID: 17485564

7

Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo.

Vlaming ML, van Esch A, Pala Z, Wagenaar E, van de Wetering K, van Tellingen O, Schinkel AH. Vlaming ML, et al. Mol Cancer Ther. 2009 Dec;8(12):3350-9. doi: 10.1158/1535-7163.MCT-09-0668. Mol Cancer Ther. 2009. PMID: 19996279

8

Impact of abcc2 [multidrug resistance-associated protein (MRP) 2], abcc3 (MRP3), and abcg2 (breast cancer resistance protein) on the oral pharmacokinetics of methotrexate and its main metabolite 7-hydroxymethotrexate.

Vlaming ML, van Esch A, van de Steeg E, Pala Z, Wagenaar E, van Tellingen O, Schinkel AH. Vlaming ML, et al. Drug Metab Dispos. 2011 Aug;39(8):1338-44. doi: 10.1124/dmd.111.038794. Epub 2011 May 12. Drug Metab Dispos. 2011. PMID: 21566011

9

P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 determine the pharmacokinetics of etoposide.

Lagas JS, Fan L, Wagenaar E, Vlaming ML, van Tellingen O, Beijnen JH, Schinkel AH. Lagas JS, et al. Among authors: vlaming ml. Clin Cancer Res. 2010 Jan 1;16(1):130-40. doi: 10.1158/1078-0432.CCR-09-1321. Epub 2009 Dec 22. Clin Cancer Res. 2010. PMID: 20028753

10

Bcrp1;Mdr1a/b;Mrp2 combination knockout mice: altered disposition of the dietary carcinogen PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its genotoxic metabolites.

Vlaming ML, Teunissen SF, van de Steeg E, van Esch A, Wagenaar E, Brunsveld L, de Greef TF, Rosing H, Schellens JH, Beijnen JH, Schinkel AH. Vlaming ML, et al. Mol Pharmacol. 2014 Mar;85(3):520-30. doi: 10.1124/mol.113.088823. Epub 2013 Dec 13. Mol Pharmacol. 2014. PMID: 24334255

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