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Mesyl phosphoramidate backbone modified antisense oligonucleotides targeting miR-21 with enhanced in vivo therapeutic potency.
Patutina OA, Gaponova Miroshnichenko SK, Sen'kova AV, Savin IA, Gladkikh DV, Burakova EA, Fokina AA, Maslov MA, Shmendel' EV, Wood MJA, Vlassov VV, Altman S, Stetsenko DA, Zenkova MA. Patutina OA, et al. Among authors: vlassov vv. Proc Natl Acad Sci U S A. 2020 Dec 22;117(51):32370-32379. doi: 10.1073/pnas.2016158117. Epub 2020 Dec 7. Proc Natl Acad Sci U S A. 2020. PMID: 33288723 Free PMC article.
Invasion of strongly binding oligonucleotides into tRNA structure.
Petyuk V, Serikov R, Tolstikov V, Potapov V, Giege R, Zenkova M, Vlassov V. Petyuk V, et al. Nucleosides Nucleotides Nucleic Acids. 2000 Jul;19(7):1145-58. doi: 10.1080/15257770008035037. Nucleosides Nucleotides Nucleic Acids. 2000. PMID: 10999254
Catalytic DNA and RNA for targeting MDR1 mRNA.
Kuznetsova M, Fokina A, Lukin M, Repkova M, Venyaminova A, Vlassov V. Kuznetsova M, et al. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1521-3. doi: 10.1081/ncn-120023025. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565457
286 results