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Novel 2-[(benzylamino)methyl]pyrrolidine-3,4-diol derivatives as alpha-mannosidase inhibitors and with antitumor activities against hematological and solid malignancies.
Bello C, Cea M, Dal Bello G, Garuti A, Rocco I, Cirmena G, Moran E, Nahimana A, Duchosal MA, Fruscione F, Pronzato P, Grossi F, Patrone F, Ballestrero A, Dupuis M, Sordat B, Nencioni A, Vogel P. Bello C, et al. Among authors: vogel p. Bioorg Med Chem. 2010 May 1;18(9):3320-34. doi: 10.1016/j.bmc.2010.03.009. Epub 2010 Mar 9. Bioorg Med Chem. 2010. PMID: 20346684
Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols.
Bello C, Dal Bello G, Cea M, Nahimana A, Aubry D, Garuti A, Motta G, Moran E, Fruscione F, Pronzato P, Grossi F, Patrone F, Ballestrero A, Dupuis M, Sordat B, Zimmermann K, Loretan J, Wartmann M, Duchosal MA, Nencioni A, Vogel P. Bello C, et al. Among authors: vogel p. Bioorg Med Chem. 2011 Dec 15;19(24):7720-7. doi: 10.1016/j.bmc.2011.07.053. Epub 2011 Jul 30. Bioorg Med Chem. 2011. PMID: 22079865
1,2,3-Triazoles as inhibitors of indoleamine 2,3-dioxygenase 2 (IDO2).
Röhrig UF, Majjigapu SR, Caldelari D, Dilek N, Reichenbach P, Ascencao K, Irving M, Coukos G, Vogel P, Zoete V, Michielin O. Röhrig UF, et al. Among authors: vogel p. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4330-3. doi: 10.1016/j.bmcl.2016.07.031. Epub 2016 Jul 16. Bioorg Med Chem Lett. 2016. PMID: 27469130
Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells.
Bello C, Bai J, Zambron BK, Elías-Rodríguez P, Gajate C, Robina I, Caffa I, Cea M, Montecucco F, Nencioni A, Nahimana A, Aubry D, Breton C, Duchosal MA, Mollinedo F, Vogel P. Bello C, et al. Among authors: vogel p. Eur J Med Chem. 2018 Apr 25;150:457-478. doi: 10.1016/j.ejmech.2018.02.086. Epub 2018 Mar 2. Eur J Med Chem. 2018. PMID: 29547833
Inhibition Mechanisms of Indoleamine 2,3-Dioxygenase 1 (IDO1).
Röhrig UF, Reynaud A, Majjigapu SR, Vogel P, Pojer F, Zoete V. Röhrig UF, et al. Among authors: vogel p. J Med Chem. 2019 Oct 10;62(19):8784-8795. doi: 10.1021/acs.jmedchem.9b00942. Epub 2019 Sep 26. J Med Chem. 2019. PMID: 31525930
880 results