MiR-574-5p activates human TLR8 to promote autoimmune signaling and lupus.
Wang T, Song D, Li X, Luo Y, Yang D, Liu X, Kong X, Xing Y, Bi S, Zhang Y, Hu T, Zhang Y, Dai S, Shao Z, Chen D, Hou J, Ballestar E, Cai J, Zheng F, Yang JY.
Wang T, et al.
Cell Commun Signal. 2024 Apr 8;22(1):220. doi: 10.1186/s12964-024-01601-1.
Cell Commun Signal. 2024.
PMID: 38589923
Free PMC article.
These responses include the overproduction of cytokines and interferons, the activation of STAT1 signaling and B lymphocytes, and the production of autoantigens. In a transgenic mouse model, the induction of miR-574-5p overexpression is associated with increased secretion …
These responses include the overproduction of cytokines and interferons, the activation of STAT1 signaling and B lymphocytes, and the …