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Expression of human thrombomodulin on porcine endothelial cells can reduce platelet aggregation but did not reduce activation of complement or endothelium - an experimental study.
Ramackers W, Rataj D, Werwitzke S, Bergmann S, Winkler M, Wünsch A, Bähr A, Wolf E, Klymiuk N, Ayares D, Tiede A. Ramackers W, et al. Among authors: wunsch a. Transpl Int. 2020 Apr;33(4):437-449. doi: 10.1111/tri.13573. Epub 2020 Feb 9. Transpl Int. 2020. PMID: 31926034 Free article.
Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs.
Bähr A, Käser T, Kemter E, Gerner W, Kurome M, Baars W, Herbach N, Witter K, Wünsch A, Talker SC, Kessler B, Nagashima H, Saalmüller A, Schwinzer R, Wolf E, Klymiuk N. Bähr A, et al. Among authors: wunsch a. PLoS One. 2016 May 13;11(5):e0155676. doi: 10.1371/journal.pone.0155676. eCollection 2016. PLoS One. 2016. PMID: 27175998 Free PMC article.
Gene Editing in Primary Cells of Cattle and Pig.
Vochozkova P, Simmet K, Jemiller EM, Wünsch A, Klymiuk N. Vochozkova P, et al. Among authors: wunsch a. Methods Mol Biol. 2019;1961:271-289. doi: 10.1007/978-1-4939-9170-9_17. Methods Mol Biol. 2019. PMID: 30912052
First inducible transgene expression in porcine large animal models.
Klymiuk N, Böcker W, Schönitzer V, Bähr A, Radic T, Fröhlich T, Wünsch A, Keßler B, Kurome M, Schilling E, Herbach N, Wanke R, Nagashima H, Mutschler W, Arnold GJ, Schwinzer R, Schieker M, Wolf E. Klymiuk N, et al. Among authors: wunsch a. FASEB J. 2012 Mar;26(3):1086-99. doi: 10.1096/fj.11-185041. Epub 2011 Dec 1. FASEB J. 2012. PMID: 22138035
Permanent neonatal diabetes in INS(C94Y) transgenic pigs.
Renner S, Braun-Reichhart C, Blutke A, Herbach N, Emrich D, Streckel E, Wünsch A, Kessler B, Kurome M, Bähr A, Klymiuk N, Krebs S, Puk O, Nagashima H, Graw J, Blum H, Wanke R, Wolf E. Renner S, et al. Among authors: wunsch a. Diabetes. 2013 May;62(5):1505-11. doi: 10.2337/db12-1065. Epub 2012 Dec 28. Diabetes. 2013. PMID: 23274907 Free PMC article.
Mild maternal hyperglycemia in INSC93S transgenic pigs causes impaired glucose tolerance and metabolic alterations in neonatal offspring.
Renner S, Martins AS, Streckel E, Braun-Reichhart C, Backman M, Prehn C, Klymiuk N, Bähr A, Blutke A, Landbrecht-Schessl C, Wünsch A, Kessler B, Kurome M, Hinrichs A, Koopmans SJ, Krebs S, Kemter E, Rathkolb B, Nagashima H, Blum H, Ritzmann M, Wanke R, Aigner B, Adamski J, Hrabě de Angelis M, Wolf E. Renner S, et al. Among authors: wunsch a. Dis Model Mech. 2019 Aug 12;12(8):dmm039156. doi: 10.1242/dmm.039156. Dis Model Mech. 2019. PMID: 31308048 Free PMC article.
Transgenic pigs as models for translational biomedical research.
Aigner B, Renner S, Kessler B, Klymiuk N, Kurome M, Wünsch A, Wolf E. Aigner B, et al. Among authors: wunsch a. J Mol Med (Berl). 2010 Jul;88(7):653-64. doi: 10.1007/s00109-010-0610-9. Epub 2010 Mar 26. J Mol Med (Berl). 2010. PMID: 20339830 Review.
151 results