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Year Number of Results
1989 1
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1993 1
1997 1
1999 1
2001 2
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2005 3
2006 4
2007 2
2008 2
2009 1
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2011 4
2012 9
2013 9
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157 results

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Page 1
WLS-Wnt signaling promotes neuroendocrine prostate cancer.
Bland T, Wang J, Yin L, Pu T, Li J, Gao J, Lin TP, Gao AC, Wu BJ. Bland T, et al. iScience. 2021 Jan 1;24(1):101970. doi: 10.1016/j.isci.2020.101970. eCollection 2021 Jan 22. iScience. 2021. PMID: 33437943 Free PMC article.
Neuroendocrine prostate cancer (NEPC) is a lethal prostate cancer subtype arising as a consequence of more potent androgen receptor (AR) targeting in castration-resistant prostate cancer (CRPC). ...These findings collectively characterize the contribution of …
Neuroendocrine prostate cancer (NEPC) is a lethal prostate cancer subtype arising as a consequence of more potent androgen rec …
WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism.
Wang LT, Lin MH, Liu KY, Chiou SS, Wang SN, Chai CY, Tseng LW, Chiou HC, Wang HC, Yokoyama KK, Hsu SH, Huang SK. Wang LT, et al. Autophagy. 2021 Dec;17(12):4202-4217. doi: 10.1080/15548627.2021.1907516. Epub 2021 Apr 14. Autophagy. 2021. PMID: 33853474 Free PMC article.
In fact, WLS was discovered to integrate a protein complex in N-glycan-dependent and WLS domain-selective manners, comprising ER stress sensors and lectin chaperones. ...Consequently, DC-specific wls-null mice were unable to develop both Th1-, Th2- and Th17-a …
In fact, WLS was discovered to integrate a protein complex in N-glycan-dependent and WLS domain-selective manners, comprising …
Wls promotes the proliferation of breast cancer cells via Wnt signaling.
Lu D, Li Y, Liu QR, Wu Q, Zhang H, Xie P, Wang Q. Lu D, et al. Med Oncol. 2015 May;32(5):140. doi: 10.1007/s12032-015-0585-z. Epub 2015 Mar 24. Med Oncol. 2015. PMID: 25801232
However, the biological significance of Wls in breast cancer progression has not been clarified. In this study, we show for the first time that Wls is an important molecule related to breast cancer. ...Therefore, Wls could be a novel therapeutic …
However, the biological significance of Wls in breast cancer progression has not been clarified. In this study, we show for th …
Wntless (Wls): A Prognostic Index for Progression and Patient Survival of Breast Cancer.
Zheng D, Jiang C, Yan N, Miao Y, Wang K, Gao G, Jiao Y, Zhang X, He M, Yang Z. Zheng D, et al. Onco Targets Ther. 2020 Dec 8;13:12649-12659. doi: 10.2147/OTT.S265324. eCollection 2020. Onco Targets Ther. 2020. PMID: 33335405 Free PMC article.
While numerous researches have demonstrated that aberrations in Wnt/beta-catenin expression lead to tumorigenesis and progression in many cancer types, the effects of Wls in breast cancer (BC) are less studied. ...Bioinformatics analysis was used to reveal th …
While numerous researches have demonstrated that aberrations in Wnt/beta-catenin expression lead to tumorigenesis and progression in many …
The function of Wls in ovarian development.
Chen L, Zhang W, Huang R, Miao X, Li J, Yu D, Li Y, Hsu W, Qiu M, Zhang Z, Li F. Chen L, et al. Mol Cell Endocrinol. 2021 Feb 15;522:111142. doi: 10.1016/j.mce.2020.111142. Epub 2021 Jan 7. Mol Cell Endocrinol. 2021. PMID: 33359762
To study the function of Wls, the Amhr2(tm3(cre)Bhr) strain was used to target deletion of Wls in granulosa cells. The deletion of Wls caused a significant decrease in the fertility of Wls(Amhr2-Cre) female mice. ...
To study the function of Wls, the Amhr2(tm3(cre)Bhr) strain was used to target deletion of Wls in granulosa cells. The deletio …
Autocrine Canonical Wnt Signaling Primes Noncanonical Signaling through ROR1 in Metastatic Castration-Resistant Prostate Cancer.
Ma F, Arai S, Wang K, Calagua C, Yuan AR, Poluben L, Gu Z, Russo JW, Einstein DJ, Ye H, He MX, Liu Y, Van Allen E, Sowalsky AG, Bhasin MK, Yuan X, Balk SP. Ma F, et al. Cancer Res. 2022 Apr 15;82(8):1518-1533. doi: 10.1158/0008-5472.CAN-21-1807. Cancer Res. 2022. PMID: 35131873 Free PMC article.
Tumor cell upregulation of the Wnt transporter Wntless (WLS) was strongly associated with Wnt/beta-catenin pathway activity in primary prostate cancer but also associated with both canonical and noncanonical Wnt signaling in mCRPC. IHC confirmed tumor cell WLS …
Tumor cell upregulation of the Wnt transporter Wntless (WLS) was strongly associated with Wnt/beta-catenin pathway activity in primar …
RAB21 controls autophagy and cellular energy homeostasis by regulating retromer-mediated recycling of SLC2A1/GLUT1.
Pei Y, Lv S, Shi Y, Jia J, Ma M, Han H, Zhang R, Tan J, Zhang X. Pei Y, et al. Autophagy. 2023 Apr;19(4):1070-1086. doi: 10.1080/15548627.2022.2114271. Epub 2022 Aug 21. Autophagy. 2023. PMID: 35993307 Free PMC article.
Functionally, RAB21 depletion sensitizes cancer cells to energy stress and inhibits tumor growth in vivo, suggesting an oncogenic role for RAB21. Overall, our study illuminates the role of RAB21 in regulating endosomal dynamics and maintaining cellular energy homeostasis a …
Functionally, RAB21 depletion sensitizes cancer cells to energy stress and inhibits tumor growth in vivo, suggesting an oncogenic rol …
Bariatric surgery in patients with breast and endometrial cancer in California: population-based prevalence and survival.
Lee E, Kawaguchi ES, Zhang J, Kim SE, Deapen D, Liu L, Sheidaee N, Hwang AE, Kang I, Sandhu K, Ursin G, Wu AH, Garcia AA. Lee E, et al. Surg Obes Relat Dis. 2022 Jan;18(1):42-52. doi: 10.1016/j.soard.2021.09.017. Epub 2021 Sep 28. Surg Obes Relat Dis. 2022. PMID: 34740554 Free PMC article.
However, the prevalence and prognostic impact of bariatric surgery, or weight loss surgery (WLS), among patients with cancer are not known. OBJECTIVES: We investigated the population-based prevalence of WLS in women with breast or endometrial cancer an …
However, the prevalence and prognostic impact of bariatric surgery, or weight loss surgery (WLS), among patients with cancer a …
Wls Expression Correlates with Tumor Differentiation and TNM Stage in Hepatocellular Carcinoma.
Zhou C, Sun Y, Guo S, Chen X, Bao G, Wang J. Zhou C, et al. Dig Dis Sci. 2018 Jan;63(1):166-172. doi: 10.1007/s10620-017-4823-4. Epub 2017 Nov 10. Dig Dis Sci. 2018. PMID: 29127606
Wntless (Wls) is a key modulator of Wnt protein secretion and is overexpressed in various human cancers. ...Twenty-eight out of 84 samples (33.3%) were negative or weakly (score 0) expressed Wls, 38 out of 84 (45.2%) moderately (1+) expressed Wls, and …
Wntless (Wls) is a key modulator of Wnt protein secretion and is overexpressed in various human cancers. ...Twenty-eight out o …
157 results