Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1954 1
1972 3
1973 4
1974 1
1976 3
1977 1
1979 5
1980 2
1981 1
1982 4
1983 5
1984 3
1985 3
1986 3
1987 3
1988 15
1989 5
1990 7
1991 7
1992 6
1993 3
1994 13
1995 15
1996 12
1997 9
1998 15
1999 8
2000 9
2001 8
2002 12
2003 6
2004 9
2005 8
2006 17
2007 8
2008 14
2009 10
2010 13
2011 6
2012 10
2013 8
2014 19
2015 16
2016 15
2017 14
2018 10
2019 16
2020 16
2021 23
2022 13
2023 10
2024 11

Text availability

Article attribute

Article type

Publication date

Search Results

429 results

Results by year

Filters applied: . Clear all
Page 1
Membrane Interaction of the Glycosyltransferase WaaG.
Liebau J, Pettersson P, Szpryngiel S, Mäler L. Liebau J, et al. Biophys J. 2015 Aug 4;109(3):552-63. doi: 10.1016/j.bpj.2015.06.036. Biophys J. 2015. PMID: 26244737 Free PMC article.
We found that the membrane interaction of WaaG is conferred at least in part by MIR-WaaG and that electrostatic interactions play a key role in binding. Moreover, we propose a mechanism of anchoring WaaG to the inner membrane of E. coli, where the central par …
We found that the membrane interaction of WaaG is conferred at least in part by MIR-WaaG and that electrostatic interactions p …
A Lead-Based Fragment Library Screening of the Glycosyltransferase WaaG from Escherichia coli.
Riu F, Ruda A, Engström O, Muheim C, Mobarak H, Ståhle J, Kosma P, Carta A, Daley DO, Widmalm G. Riu F, et al. Pharmaceuticals (Basel). 2022 Feb 9;15(2):209. doi: 10.3390/ph15020209. Pharmaceuticals (Basel). 2022. PMID: 35215321 Free PMC article.
Glucosyl transferase I (WaaG) in E. coli catalyzes the transfer of an alpha-d-glucosyl group to the inner core of the lipopolysaccharide (LPS) and plays an important role in the biogenesis of the outer membrane. ...In the presence of UDP-Glc(2-), the best-docked pose of di …
Glucosyl transferase I (WaaG) in E. coli catalyzes the transfer of an alpha-d-glucosyl group to the inner core of the lipopolysacchar …
New insights into the membrane association mechanism of the glycosyltransferase WaaG from Escherichia coli.
Liebau J, Fu B, Brown C, Mäler L. Liebau J, et al. Biochim Biophys Acta Biomembr. 2018 Mar;1860(3):683-690. doi: 10.1016/j.bbamem.2017.12.004. Epub 2017 Dec 8. Biochim Biophys Acta Biomembr. 2018. PMID: 29225173 Free article.
Here, we studied the applicability of this model to the glycosyltransferase WaaG. WaaG is involved in the synthesis of lipopolysaccharides (LPS) in Gram-negative bacteria and was previously categorized as a monotopic GT. We analyzed the binding of WaaG to mem …
Here, we studied the applicability of this model to the glycosyltransferase WaaG. WaaG is involved in the synthesis of lipopol …
Identification of a Fragment-Based Scaffold that Inhibits the Glycosyltransferase WaaG from Escherichia coli.
Muheim C, Bakali A, Engström O, Wieslander Å, Daley DO, Widmalm G. Muheim C, et al. Antibiotics (Basel). 2016 Jan 28;5(1):10. doi: 10.3390/antibiotics5010010. Antibiotics (Basel). 2016. PMID: 27025525 Free PMC article.
WaaG is a glycosyltransferase that is involved in the biosynthesis of lipopolysaccharide in Gram-negative bacteria. ...Herein, we establish an activity assay for WaaG using (14)C-labeled UDP-glucose and LPS purified from a waaG strain of Escherichia coli. ...
WaaG is a glycosyltransferase that is involved in the biosynthesis of lipopolysaccharide in Gram-negative bacteria. ...Herein, we est …
Structural and functional insights into the Pseudomonas aeruginosa glycosyltransferase WaaG and the implications for lipopolysaccharide biosynthesis.
Scaletti ER, Pettersson P, Patrick J, Shilling PJ, Westergren RG, Daley DO, Mäler L, Widmalm G, Stenmark P. Scaletti ER, et al. J Biol Chem. 2023 Oct;299(10):105256. doi: 10.1016/j.jbc.2023.105256. Epub 2023 Sep 15. J Biol Chem. 2023. PMID: 37716703 Free PMC article.
The glycosyltransferase WaaG in Pseudomonas aeruginosa (PaWaaG) is involved in the synthesis of the core region of lipopolysaccharides. ...
The glycosyltransferase WaaG in Pseudomonas aeruginosa (PaWaaG) is involved in the synthesis of the core region of lipopolysaccharide …
Mutation of the lipopolysaccharide core glycosyltransferase encoded by waaG destabilizes the outer membrane of Escherichia coli by interfering with core phosphorylation.
Yethon JA, Vinogradov E, Perry MB, Whitfield C. Yethon JA, et al. J Bacteriol. 2000 Oct;182(19):5620-3. doi: 10.1128/JB.182.19.5620-5623.2000. J Bacteriol. 2000. PMID: 10986272 Free PMC article.
In Escherichia coli, phosphoryl substituents in the lipopolysaccharide core region are essential for outer membrane stability. Mutation of the core glucosyltransferase encoded by waaG (formerly rfaG) resulted in lipopolysaccharide truncated immediately after the inner core …
In Escherichia coli, phosphoryl substituents in the lipopolysaccharide core region are essential for outer membrane stability. Mutation of t …
Small molecules containing hetero-bicyclic ring systems compete with UDP-Glc for binding to WaaG glycosyltransferase.
Landström J, Persson K, Rademacher C, Lundborg M, Wakarchuk W, Peters T, Widmalm G. Landström J, et al. Glycoconj J. 2012 Oct;29(7):491-502. doi: 10.1007/s10719-012-9411-4. Epub 2012 Jun 19. Glycoconj J. 2012. PMID: 22711644
The alpha-1,3-glucosyltransferase WaaG is involved in the synthesis of the core region of lipopolysaccharides in E. coli. ...Molecular dynamics simulations of WaaG were carried out with and without bound UDP and revealed structural changes compared to the crystal st …
The alpha-1,3-glucosyltransferase WaaG is involved in the synthesis of the core region of lipopolysaccharides in E. coli. ...Molecula …
429 results