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E-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation.
Pruenster M, Immler R, Roth J, Kuchler T, Bromberger T, Napoli M, Nussbaumer K, Rohwedder I, Wackerbarth LM, Piantoni C, Hennis K, Fink D, Kallabis S, Schroll T, Masgrau-Alsina S, Budke A, Liu W, Vestweber D, Wahl-Schott C, Roth J, Meissner F, Moser M, Vogl T, Hornung V, Broz P, Sperandio M. Pruenster M, et al. Among authors: wackerbarth lm. Nat Immunol. 2023 Dec;24(12):2021-2031. doi: 10.1038/s41590-023-01656-1. Epub 2023 Oct 30. Nat Immunol. 2023. PMID: 37903858 Free PMC article.
A20 and the noncanonical NF-κB pathway are key regulators of neutrophil recruitment during fetal ontogeny.
Rohwedder I, Wackerbarth LM, Heinig K, Ballweg A, Altstätter J, Ripphahn M, Nussbaum C, Salvermoser M, Bierschenk S, Straub T, Gunzer M, Schmidt-Supprian M, Kolben T, Schulz C, Ma A, Walzog B, Heinig M, Sperandio M. Rohwedder I, et al. Among authors: wackerbarth lm. JCI Insight. 2023 Feb 22;8(4):e155968. doi: 10.1172/jci.insight.155968. JCI Insight. 2023. PMID: 36633909 Free PMC article.
MST1 controls murine neutrophil homeostasis via the G-CSFR/STAT3 axis.
Masgrau-Alsina S, Wackerbarth LM, Lim DS, Sperandio M. Masgrau-Alsina S, et al. Among authors: wackerbarth lm. Front Immunol. 2022 Dec 23;13:1038936. doi: 10.3389/fimmu.2022.1038936. eCollection 2022. Front Immunol. 2022. PMID: 36618429 Free PMC article.
Impaired microtubule dynamics contribute to microthrombocytopenia in RhoB-deficient mice.
Englert M, Aurbach K, Becker IC, Gerber A, Heib T, Wackerbarth LM, Kusch C, Mott K, Araujo GHM, Baig AA, Dütting S, Knaus UG, Stigloher C, Schulze H, Nieswandt B, Pleines I, Nagy Z. Englert M, et al. Among authors: wackerbarth lm. Blood Adv. 2022 Sep 13;6(17):5184-5197. doi: 10.1182/bloodadvances.2021006545. Blood Adv. 2022. PMID: 35819450 Free PMC article.
RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes.
Heib T, Hermanns HM, Manukjan G, Englert M, Kusch C, Becker IC, Gerber A, Wackerbarth LM, Burkard P, Dandekar T, Balkenhol J, Jahn D, Beck S, Meub M, Dütting S, Stigloher C, Sauer M, Cherpokova D, Schulze H, Brakebusch C, Nieswandt B, Nagy Z, Pleines I. Heib T, et al. Among authors: wackerbarth lm. Cell Rep. 2021 May 11;35(6):109102. doi: 10.1016/j.celrep.2021.109102. Cell Rep. 2021. PMID: 33979620 Free article.
Actin/microtubule crosstalk during platelet biogenesis in mice is critically regulated by Twinfilin1 and Cofilin1.
Becker IC, Scheller I, Wackerbarth LM, Beck S, Heib T, Aurbach K, Manukjan G, Gross C, Spindler M, Nagy Z, Witke W, Lappalainen P, Bender M, Schulze H, Pleines I, Nieswandt B. Becker IC, et al. Among authors: wackerbarth lm. Blood Adv. 2020 May 26;4(10):2124-2134. doi: 10.1182/bloodadvances.2019001303. Blood Adv. 2020. PMID: 32407474 Free PMC article.