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Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.
Inami Y, Waguri S, Sakamoto A, Kouno T, Nakada K, Hino O, Watanabe S, Ando J, Iwadate M, Yamamoto M, Lee MS, Tanaka K, Komatsu M. Inami Y, et al. Among authors: waguri s. J Cell Biol. 2011 Apr 18;193(2):275-84. doi: 10.1083/jcb.201102031. Epub 2011 Apr 11. J Cell Biol. 2011. PMID: 21482715 Free PMC article.
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice.
Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, Tanida I, Ezaki J, Mizushima N, Ohsumi Y, Uchiyama Y, Kominami E, Tanaka K, Chiba T. Komatsu M, et al. Among authors: waguri s. J Cell Biol. 2005 May 9;169(3):425-34. doi: 10.1083/jcb.200412022. Epub 2005 May 2. J Cell Biol. 2005. PMID: 15866887 Free PMC article.
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.
Komatsu M, Waguri S, Koike M, Sou YS, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E, Tanaka K. Komatsu M, et al. Among authors: waguri s. Cell. 2007 Dec 14;131(6):1149-63. doi: 10.1016/j.cell.2007.10.035. Cell. 2007. PMID: 18083104 Free article.
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.
Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M. Komatsu M, et al. Among authors: waguri s. Nat Cell Biol. 2010 Mar;12(3):213-23. doi: 10.1038/ncb2021. Epub 2010 Feb 21. Nat Cell Biol. 2010. PMID: 20173742
145 results