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Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1.
Lavery GG, Zielinska AE, Gathercole LL, Hughes B, Semjonous N, Guest P, Saqib K, Sherlock M, Reynolds G, Morgan SA, Tomlinson JW, Walker EA, Rabbitt EH, Stewart PM. Lavery GG, et al. Among authors: walker ea. Endocrinology. 2012 Jul;153(7):3236-48. doi: 10.1210/en.2012-1019. Epub 2012 May 3. Endocrinology. 2012. PMID: 22555437 Free PMC article.
Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency.
Draper N, Walker EA, Bujalska IJ, Tomlinson JW, Chalder SM, Arlt W, Lavery GG, Bedendo O, Ray DW, Laing I, Malunowicz E, White PC, Hewison M, Mason PJ, Connell JM, Shackleton CH, Stewart PM. Draper N, et al. Among authors: walker ea. Nat Genet. 2003 Aug;34(4):434-9. doi: 10.1038/ng1214. Nat Genet. 2003. PMID: 12858176
443 results