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Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.
Yaseen S, Demopulos G, Dudler T, Yabuki M, Wood CL, Cummings WJ, Tjoelker LW, Fujita T, Sacks S, Garred P, Andrew P, Sim RB, Lachmann PJ, Wallis R, Lynch N, Schwaeble WJ. Yaseen S, et al. Among authors: wallis r. FASEB J. 2017 May;31(5):2210-2219. doi: 10.1096/fj.201601306R. Epub 2017 Feb 10. FASEB J. 2017. PMID: 28188176
., Tjoelker, L. W., Fujita, T., Sacks, S., Garred, P., Andrew, P., Sim, R. B., Lachmann, P. J., Wallis, R., Lynch, N., Schwaeble, W. J. ...
., Tjoelker, L. W., Fujita, T., Sacks, S., Garred, P., Andrew, P., Sim, R. B., Lachmann, P. J., Wallis, R., Lynch, N., …
Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation.
Venkatraman Girija U, Gingras AR, Marshall JE, Panchal R, Sheikh MA, Harper JA, Gál P, Schwaeble WJ, Mitchell DA, Moody PC, Wallis R. Venkatraman Girija U, et al. Among authors: wallis r. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13916-20. doi: 10.1073/pnas.1311113110. Epub 2013 Aug 6. Proc Natl Acad Sci U S A. 2013. PMID: 23922389 Free PMC article.
Surface properties: Immune attack on nanoparticles.
Sim RB, Wallis R. Sim RB, et al. Among authors: wallis r. Nat Nanotechnol. 2011 Feb;6(2):80-1. doi: 10.1038/nnano.2011.4. Nat Nanotechnol. 2011. PMID: 21293484 No abstract available.
516 results