Waltenberger B - Search Results

1

Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening.

Temml V, Garscha U, Romp E, Schubert G, Gerstmeier J, Kutil Z, Matuszczak B, Waltenberger B, Stuppner H, Werz O, Schuster D. Temml V, et al. Among authors: waltenberger b. Sci Rep. 2017 Feb 20;7:42751. doi: 10.1038/srep42751. Sci Rep. 2017. PMID: 28218273 Free PMC article.

2

Pharmacophore modeling and virtual screening for novel acidic inhibitors of microsomal prostaglandin E₂ synthase-1 (mPGES-1).

Waltenberger B, Wiechmann K, Bauer J, Markt P, Noha SM, Wolber G, Rollinger JM, Werz O, Schuster D, Stuppner H. Waltenberger B, et al. J Med Chem. 2011 May 12;54(9):3163-74. doi: 10.1021/jm101309g. Epub 2011 Apr 20. J Med Chem. 2011. PMID: 21466167 Free PMC article.

3

Discovery of Potent Soluble Epoxide Hydrolase (sEH) Inhibitors by Pharmacophore-Based Virtual Screening.

Waltenberger B, Garscha U, Temml V, Liers J, Werz O, Schuster D, Stuppner H. Waltenberger B, et al. J Chem Inf Model. 2016 Apr 25;56(4):747-62. doi: 10.1021/acs.jcim.5b00592. Epub 2016 Apr 4. J Chem Inf Model. 2016. PMID: 26882208

4

Discovery of depsides and depsidones from lichen as potent inhibitors of microsomal prostaglandin E2 synthase-1 using pharmacophore models.

Bauer J, Waltenberger B, Noha SM, Schuster D, Rollinger JM, Boustie J, Chollet M, Stuppner H, Werz O. Bauer J, et al. Among authors: waltenberger b. ChemMedChem. 2012 Dec;7(12):2077-81. doi: 10.1002/cmdc.201200345. Epub 2012 Oct 25. ChemMedChem. 2012. PMID: 23109349 Free PMC article.

5

Imbricaric acid and perlatolic acid: multi-targeting anti-inflammatory depsides from Cetrelia monachorum.

Oettl SK, Gerstmeier J, Khan SY, Wiechmann K, Bauer J, Atanasov AG, Malainer C, Awad EM, Uhrin P, Heiss EH, Waltenberger B, Remias D, Breuss JM, Boustie J, Dirsch VM, Stuppner H, Werz O, Rollinger JM. Oettl SK, et al. Among authors: waltenberger b. PLoS One. 2013 Oct 9;8(10):e76929. doi: 10.1371/journal.pone.0076929. eCollection 2013. PLoS One. 2013. PMID: 24130812 Free PMC article.

6

Plumericin inhibits proliferation of vascular smooth muscle cells by blocking STAT3 signaling via S-glutathionylation.

Heiss EH, Liu R, Waltenberger B, Khan S, Schachner D, Kollmann P, Zimmermann K, Cabaravdic M, Uhrin P, Stuppner H, Breuss JM, Atanasov AG, Dirsch VM. Heiss EH, et al. Among authors: waltenberger b. Sci Rep. 2016 Feb 9;6:20771. doi: 10.1038/srep20771. Sci Rep. 2016. PMID: 26858089 Free PMC article.

7

A combinatorial approach for the discovery of cytochrome P450 2D6 inhibitors from nature.

Hochleitner J, Akram M, Ueberall M, Davis RA, Waltenberger B, Stuppner H, Sturm S, Ueberall F, Gostner JM, Schuster D. Hochleitner J, et al. Among authors: waltenberger b. Sci Rep. 2017 Aug 14;7(1):8071. doi: 10.1038/s41598-017-08404-0. Sci Rep. 2017. PMID: 28808272 Free PMC article.

8

Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction.

Mayr F, Möller G, Garscha U, Fischer J, Rodríguez Castaño P, Inderbinen SG, Temml V, Waltenberger B, Schwaiger S, Hartmann RW, Gege C, Martens S, Odermatt A, Pandey AV, Werz O, Adamski J, Stuppner H, Schuster D. Mayr F, et al. Among authors: waltenberger b. Int J Mol Sci. 2020 Sep 26;21(19):7102. doi: 10.3390/ijms21197102. Int J Mol Sci. 2020. PMID: 32993084 Free PMC article.

9

Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase.

Pein H, Ville A, Pace S, Temml V, Garscha U, Raasch M, Alsabil K, Viault G, Dinh CP, Guilet D, Troisi F, Neukirch K, König S, Bilancia R, Waltenberger B, Stuppner H, Wallert M, Lorkowski S, Weinigel C, Rummler S, Birringer M, Roviezzo F, Sautebin L, Helesbeux JJ, Séraphin D, Mosig AS, Schuster D, Rossi A, Richomme P, Werz O, Koeberle A. Pein H, et al. Among authors: waltenberger b. Nat Commun. 2018 Sep 20;9(1):3834. doi: 10.1038/s41467-018-06158-5. Nat Commun. 2018. PMID: 30237488 Free PMC article.

10

Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis.

Gerstmeier J, Seegers J, Witt F, Waltenberger B, Temml V, Rollinger JM, Stuppner H, Koeberle A, Schuster D, Werz O. Gerstmeier J, et al. Among authors: waltenberger b. Front Pharmacol. 2019 Jul 17;10:797. doi: 10.3389/fphar.2019.00797. eCollection 2019. Front Pharmacol. 2019. PMID: 31379572 Free PMC article.

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