Walter J - Search Results

1

Sequential proteolytic processing of the triggering receptor expressed on myeloid cells-2 (TREM2) protein by ectodomain shedding and γ-secretase-dependent intramembranous cleavage.

Wunderlich P, Glebov K, Kemmerling N, Tien NT, Neumann H, Walter J. Wunderlich P, et al. Among authors: walter j. J Biol Chem. 2013 Nov 15;288(46):33027-36. doi: 10.1074/jbc.M113.517540. Epub 2013 Sep 27. J Biol Chem. 2013. PMID: 24078628 Free PMC article.

2

Ectodomain phosphorylation of beta-amyloid precursor protein at two distinct cellular locations.

Walter J, Capell A, Hung AY, Langen H, Schnölzer M, Thinakaran G, Sisodia SS, Selkoe DJ, Haass C. Walter J, et al. J Biol Chem. 1997 Jan 17;272(3):1896-903. doi: 10.1074/jbc.272.3.1896. J Biol Chem. 1997. PMID: 8999878 Free article.

3

Maturation and pro-peptide cleavage of beta-secretase.

Capell A, Steiner H, Willem M, Kaiser H, Meyer C, Walter J, Lammich S, Multhaup G, Haass C. Capell A, et al. Among authors: walter j. J Biol Chem. 2000 Oct 6;275(40):30849-54. doi: 10.1074/jbc.M003202200. J Biol Chem. 2000. PMID: 10801872 Free article.

4

Phosphorylation of the beta-amyloid precursor protein at the cell surface by ectocasein kinases 1 and 2.

Walter J, Schindzielorz A, Hartung B, Haass C. Walter J, et al. J Biol Chem. 2000 Aug 4;275(31):23523-9. doi: 10.1074/jbc.M002850200. J Biol Chem. 2000. PMID: 10806211 Free article.

We have shown previously that betaAPP can be phosphorylated within secretory vesicles and at the cell surface (Walter, J., Capell, A., Hung, A. Y. , Langen, H., Schnolzer, M., Thinakaran, G., Sisodia, S. S., Selkoe, D. J., and Haass, C. (1997) J. Biol. …

We have shown previously that betaAPP can be phosphorylated within secretory vesicles and at the cell surface (Walter, J., Cap …

5

A loss of function mutant of the presenilin homologue SEL-12 undergoes aberrant endoproteolysis in Caenorhabditis elegans and increases abeta 42 generation in human cells.

Okochi M, Eimer S, Bottcher A, Baumeister R, Romig H, Walter J, Capell A, Steiner H, Haass C. Okochi M, et al. Among authors: walter j. J Biol Chem. 2000 Dec 29;275(52):40925-32. doi: 10.1074/jbc.M005254200. J Biol Chem. 2000. PMID: 11013240 Free article.

6

Phosphorylation regulates intracellular trafficking of beta-secretase.

Walter J, Fluhrer R, Hartung B, Willem M, Kaether C, Capell A, Lammich S, Multhaup G, Haass C. Walter J, et al. J Biol Chem. 2001 May 4;276(18):14634-41. doi: 10.1074/jbc.M011116200. Epub 2001 Jan 29. J Biol Chem. 2001. PMID: 11278841 Free article.

7

Apical sorting of beta-secretase limits amyloid beta-peptide production.

Capell A, Meyn L, Fluhrer R, Teplow DB, Walter J, Haass C. Capell A, et al. Among authors: walter j. J Biol Chem. 2002 Feb 15;277(7):5637-43. doi: 10.1074/jbc.M109119200. Epub 2001 Dec 6. J Biol Chem. 2002. PMID: 11741885 Free article.

8

Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide.

Lammich S, Okochi M, Takeda M, Kaether C, Capell A, Zimmer AK, Edbauer D, Walter J, Steiner H, Haass C. Lammich S, et al. Among authors: walter j. J Biol Chem. 2002 Nov 22;277(47):44754-9. doi: 10.1074/jbc.M206872200. Epub 2002 Sep 9. J Biol Chem. 2002. PMID: 12223485 Free article.

9

Identification of a beta-secretase activity, which truncates amyloid beta-peptide after its presenilin-dependent generation.

Fluhrer R, Multhaup G, Schlicksupp A, Okochi M, Takeda M, Lammich S, Willem M, Westmeyer G, Bode W, Walter J, Haass C. Fluhrer R, et al. Among authors: walter j. J Biol Chem. 2003 Feb 21;278(8):5531-8. doi: 10.1074/jbc.M211485200. Epub 2002 Dec 5. J Biol Chem. 2003. PMID: 12471021 Free article.

10

Phosphorylation of presenilin 1 at the caspase recognition site regulates its proteolytic processing and the progression of apoptosis.

Fluhrer R, Friedlein A, Haass C, Walter J. Fluhrer R, et al. Among authors: walter j. J Biol Chem. 2004 Jan 16;279(3):1585-93. doi: 10.1074/jbc.M306653200. Epub 2003 Oct 22. J Biol Chem. 2004. PMID: 14576165 Free article.

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