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Curtailing FGF19's mitogenicity by suppressing its receptor dimerization ability.
Niu J, Zhao J, Wu J, Qiao G, Gu J, Zhou C, Li Q, Ying L, Wang D, Lin H, Li X, Mohammadi M, Huang Z. Niu J, et al. Among authors: wang d. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):29025-29034. doi: 10.1073/pnas.2010984117. Epub 2020 Nov 3. Proc Natl Acad Sci U S A. 2020. PMID: 33144503 Free PMC article.
FGF1ΔHBS prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression.
Wang D, Yin Y, Wang S, Zhao T, Gong F, Zhao Y, Wang B, Huang Y, Cheng Z, Zhu G, Wang Z, Wang Y, Ren J, Liang G, Li X, Huang Z. Wang D, et al. Among authors: wang z, wang y, wang s, wang b. Signal Transduct Target Ther. 2021 Mar 24;6(1):133. doi: 10.1038/s41392-021-00542-2. Signal Transduct Target Ther. 2021. PMID: 33762571 Free PMC article.
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