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Gremlin1 is a therapeutically targetable FGFR1 ligand that regulates lineage plasticity and castration resistance in prostate cancer.
Cheng C, Wang J, Xu P, Zhang K, Xin Z, Zhao H, Ji Z, Zhang M, Wang D, He Y, Jing N, Fan L, Liu K, Li F, Liu C, Gong Y, Cui S, Sun Z, Sun D, Yao X, Li H, Zhang J, Zhang P, Dong B, Xue W, Qian X, Gao WQ, Zhu HH. Cheng C, et al. Among authors: wang j, wang d. Nat Cancer. 2022 May;3(5):565-580. doi: 10.1038/s43018-022-00380-3. Epub 2022 May 27. Nat Cancer. 2022. PMID: 35624341
Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation.
He Y, Ji Z, Gong Y, Fan L, Xu P, Chen X, Miao J, Zhang K, Zhang W, Ma P, Zhao H, Cheng C, Wang D, Wang J, Jing N, Liu K, Zhang P, Dong B, Zhuang G, Fu Y, Xue W, Gao WQ, Zhu HH. He Y, et al. Among authors: wang j, wang d. Cell Rep. 2023 Feb 28;42(2):112033. doi: 10.1016/j.celrep.2023.112033. Epub 2023 Jan 31. Cell Rep. 2023. PMID: 36724072 Free article.
IL-1β Is an Androgen-Responsive Target in Macrophages for Immunotherapy of Prostate Cancer.
Wang D, Cheng C, Chen X, Wang J, Liu K, Jing N, Xu P, Xi X, Sun Y, Ji Z, Zhao H, He Y, Zhang K, Du X, Dong B, Fang Y, Zhang P, Qian X, Xue W, Gao WQ, Zhu HH. Wang D, et al. Among authors: wang j. Adv Sci (Weinh). 2023 Jun;10(17):e2206889. doi: 10.1002/advs.202206889. Epub 2023 Apr 24. Adv Sci (Weinh). 2023. PMID: 37092583 Free PMC article.
ADORA2A-driven proline synthesis triggers epigenetic reprogramming in neuroendocrine prostate and lung cancers.
Jing N, Zhang K, Chen X, Liu K, Wang J, Xiao L, Zhang W, Ma P, Xu P, Cheng C, Wang D, Zhao H, He Y, Ji Z, Xin Z, Sun Y, Zhang Y, Bao W, Gong Y, Fan L, Ji Y, Zhuang G, Wang Q, Dong B, Zhang P, Xue W, Gao WQ, Zhu HH. Jing N, et al. Among authors: wang j, wang d, wang q. J Clin Invest. 2023 Dec 15;133(24):e168670. doi: 10.1172/JCI168670. J Clin Invest. 2023. PMID: 38099497 Free PMC article.
Zeb1-controlled metabolic plasticity enables remodeling of chromatin accessibility in the development of neuroendocrine prostate cancer.
Wang D, Du G, Chen X, Wang J, Liu K, Zhao H, Cheng C, He Y, Jing N, Xu P, Bao W, Xi X, Zhang Y, Wang N, Liu Y, Sun Y, Zhang K, Zhang P, Gao WQ, Zhu HH. Wang D, et al. Among authors: wang j, wang n. Cell Death Differ. 2024 Apr 23. doi: 10.1038/s41418-024-01295-5. Online ahead of print. Cell Death Differ. 2024. PMID: 38654072
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