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The presence of Lys27 instead of Asn27 in human phospholamban promotes sarcoplasmic reticulum Ca2+-ATPase superinhibition and cardiac remodeling.
Zhao W, Yuan Q, Qian J, Waggoner JR, Pathak A, Chu G, Mitton B, Sun X, Jin J, Braz JC, Hahn HS, Marreez Y, Syed F, Pollesello P, Annila A, Wang HS, Schultz Jel J, Molkentin JD, Liggett SB, Dorn GW 2nd, Kranias EG. Zhao W, et al. Among authors: wang hs. Circulation. 2006 Feb 21;113(7):995-1004. doi: 10.1161/CIRCULATIONAHA.105.583351. Epub 2006 Feb 13. Circulation. 2006. PMID: 16476846
Sarcoplasmic reticulum calcium overloading in junctin deficiency enhances cardiac contractility but increases ventricular automaticity.
Yuan Q, Fan GC, Dong M, Altschafl B, Diwan A, Ren X, Hahn HH, Zhao W, Waggoner JR, Jones LR, Jones WK, Bers DM, Dorn GW 2nd, Wang HS, Valdivia HH, Chu G, Kranias EG. Yuan Q, et al. Among authors: wang hs. Circulation. 2007 Jan 23;115(3):300-9. doi: 10.1161/CIRCULATIONAHA.106.654699. Epub 2007 Jan 15. Circulation. 2007. PMID: 17224479
Evolution of ventricular myocyte electrophysiology.
Rosati B, Dong M, Cheng L, Liou SR, Yan Q, Park JY, Shiang E, Sanguinetti M, Wang HS, McKinnon D. Rosati B, et al. Among authors: wang hs. Physiol Genomics. 2008 Nov 12;35(3):262-72. doi: 10.1152/physiolgenomics.00159.2007. Epub 2008 Sep 2. Physiol Genomics. 2008. PMID: 18765860 Free PMC article.
1,491 results