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Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis.
Nanduri J, Makarenko V, Reddy VD, Yuan G, Pawar A, Wang N, Khan SA, Zhang X, Kinsman B, Peng YJ, Kumar GK, Fox AP, Godley LA, Semenza GL, Prabhakar NR. Nanduri J, et al. Among authors: wang n. Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2515-20. doi: 10.1073/pnas.1120600109. Epub 2012 Jan 9. Proc Natl Acad Sci U S A. 2012. PMID: 22232674 Free PMC article.
Reactive oxygen species-dependent endothelin signaling is required for augmented hypoxic sensory response of the neonatal carotid body by intermittent hypoxia.
Pawar A, Nanduri J, Yuan G, Khan SA, Wang N, Kumar GK, Prabhakar NR. Pawar A, et al. Among authors: wang n. Am J Physiol Regul Integr Comp Physiol. 2009 Mar;296(3):R735-42. doi: 10.1152/ajpregu.90490.2008. Epub 2008 Dec 24. Am J Physiol Regul Integr Comp Physiol. 2009. PMID: 19109370 Free PMC article.
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension.
Peng YJ, Nanduri J, Khan SA, Yuan G, Wang N, Kinsman B, Vaddi DR, Kumar GK, Garcia JA, Semenza GL, Prabhakar NR. Peng YJ, et al. Among authors: wang n. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):3065-70. doi: 10.1073/pnas.1100064108. Epub 2011 Jan 31. Proc Natl Acad Sci U S A. 2011. PMID: 21288809 Free PMC article.
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