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A synthetic farnesoid X receptor (FXR) agonist promotes cholesterol lowering in models of dyslipidemia.
Evans MJ, Mahaney PE, Borges-Marcucci L, Lai K, Wang S, Krueger JA, Gardell SJ, Huard C, Martinez R, Vlasuk GP, Harnish DC. Evans MJ, et al. Among authors: wang s. Am J Physiol Gastrointest Liver Physiol. 2009 Mar;296(3):G543-52. doi: 10.1152/ajpgi.90585.2008. Epub 2009 Jan 8. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19136377 Free article.
Indazole-based liver X receptor (LXR) modulators with maintained atherosclerotic lesion reduction activity but diminished stimulation of hepatic triglyceride synthesis.
Wrobel J, Steffan R, Bowen SM, Magolda R, Matelan E, Unwalla R, Basso M, Clerin V, Gardell SJ, Nambi P, Quinet E, Reminick JI, Vlasuk GP, Wang S, Feingold I, Huselton C, Bonn T, Farnegardh M, Hansson T, Nilsson AG, Wilhelmsson A, Zamaratski E, Evans MJ. Wrobel J, et al. Among authors: wang s. J Med Chem. 2008 Nov 27;51(22):7161-8. doi: 10.1021/jm800799q. J Med Chem. 2008. PMID: 18973288
Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells.
DiBlasio-Smith EA, Arai M, Quinet EM, Evans MJ, Kornaga T, Basso MD, Chen L, Feingold I, Halpern AR, Liu QY, Nambi P, Savio D, Wang S, Mounts WM, Isler JA, Slager AM, Burczynski ME, Dorner AJ, LaVallie ER. DiBlasio-Smith EA, et al. Among authors: wang s. J Transl Med. 2008 Oct 16;6:59. doi: 10.1186/1479-5876-6-59. J Transl Med. 2008. PMID: 18925943 Free PMC article. Clinical Trial.
De novo transcriptome assembly database for 100 tissues from each of seven species of domestic herbivore.
Wang Y, Huang Y, Zhen Y, Wang J, Wang L, Chen N, Wu F, Zhang L, Shen Y, Bi C, Li S, Pool K, Blache D, Maloney SK, Liu D, Yang Z, Li C, Yu X, Zhang Z, Chen Y, Xue C, Gu Y, Huang W, Yan L, Wei W, Wang Y, Zhang J, Zhang Y, Sun Y, Wang S, Zhao X, Luo C, Wang H, Ding L, Yang QY, Zhou P, Wang M. Wang Y, et al. Among authors: wang s. Sci Data. 2024 May 11;11(1):488. doi: 10.1038/s41597-024-03338-5. Sci Data. 2024. PMID: 38734729
109,238 results
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