Wang X - Search Results

1

Transcriptional and functional complexity of Shank3 provides a molecular framework to understand the phenotypic heterogeneity of SHANK3 causing autism and Shank3 mutant mice.

Wang X, Xu Q, Bey AL, Lee Y, Jiang YH. Wang X, et al. Mol Autism. 2014 Apr 25;5:30. doi: 10.1186/2040-2392-5-30. eCollection 2014. Mol Autism. 2014. PMID: 25071925 Free PMC article.

2

Autism-associated CHD8 deficiency impairs axon development and migration of cortical neurons.

Xu Q, Liu YY, Wang X, Tan GH, Li HP, Hulbert SW, Li CY, Hu CC, Xiong ZQ, Xu X, Jiang YH. Xu Q, et al. Among authors: wang x. Mol Autism. 2018 Dec 19;9:65. doi: 10.1186/s13229-018-0244-2. eCollection 2018. Mol Autism. 2018. PMID: 30574290 Free PMC article.

3

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3.

Wang X, McCoy PA, Rodriguiz RM, Pan Y, Je HS, Roberts AC, Kim CJ, Berrios J, Colvin JS, Bousquet-Moore D, Lorenzo I, Wu G, Weinberg RJ, Ehlers MD, Philpot BD, Beaudet AL, Wetsel WC, Jiang YH. Wang X, et al. Hum Mol Genet. 2011 Aug 1;20(15):3093-108. doi: 10.1093/hmg/ddr212. Epub 2011 May 10. Hum Mol Genet. 2011. PMID: 21558424 Free PMC article.

4

Therapeutic approaches for shankopathies.

Wang X, Bey AL, Chung L, Krystal AD, Jiang YH. Wang X, et al. Dev Neurobiol. 2014 Feb;74(2):123-35. doi: 10.1002/dneu.22084. Epub 2013 Oct 11. Dev Neurobiol. 2014. PMID: 23536326 Free PMC article. Review.

5

Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders.

Zhu L, Wang X, Li XL, Towers A, Cao X, Wang P, Bowman R, Yang H, Goldstein J, Li YJ, Jiang YH. Zhu L, et al. Among authors: wang x, wang p. Hum Mol Genet. 2014 Mar 15;23(6):1563-78. doi: 10.1093/hmg/ddt547. Epub 2013 Nov 1. Hum Mol Genet. 2014. PMID: 24186872 Free PMC article.

6

Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism.

Wang X, Bey AL, Katz BM, Badea A, Kim N, David LK, Duffney LJ, Kumar S, Mague SD, Hulbert SW, Dutta N, Hayrapetyan V, Yu C, Gaidis E, Zhao S, Ding JD, Xu Q, Chung L, Rodriguiz RM, Wang F, Weinberg RJ, Wetsel WC, Dzirasa K, Yin H, Jiang YH. Wang X, et al. Among authors: wang f. Nat Commun. 2016 May 10;7:11459. doi: 10.1038/ncomms11459. Nat Commun. 2016. PMID: 27161151 Free PMC article.

7

SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons.

Han Q, Kim YH, Wang X, Liu D, Zhang ZJ, Bey AL, Lay M, Chang W, Berta T, Zhang Y, Jiang YH, Ji RR. Han Q, et al. Among authors: wang x. Neuron. 2016 Dec 21;92(6):1279-1293. doi: 10.1016/j.neuron.2016.11.007. Epub 2016 Dec 1. Neuron. 2016. PMID: 27916453 Free PMC article.

8

Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers.

Pappas AL, Bey AL, Wang X, Rossi M, Kim YH, Yan H, Porkka F, Duffney LJ, Phillips SM, Cao X, Ding JD, Rodriguiz RM, Yin HH, Weinberg RJ, Ji RR, Wetsel WC, Jiang YH. Pappas AL, et al. Among authors: wang x. JCI Insight. 2017 Oct 19;2(20):e92052. doi: 10.1172/jci.insight.92052. JCI Insight. 2017. PMID: 29046483 Free PMC article.

9

Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors.

Bey AL, Wang X, Yan H, Kim N, Passman RL, Yang Y, Cao X, Towers AJ, Hulbert SW, Duffney LJ, Gaidis E, Rodriguiz RM, Wetsel WC, Yin HH, Jiang YH. Bey AL, et al. Among authors: wang x. Transl Psychiatry. 2018 Apr 27;8(1):94. doi: 10.1038/s41398-018-0142-6. Transl Psychiatry. 2018. PMID: 29700290 Free PMC article.

10

Epigenetic dysregulation of Oxtr in Tet1-deficient mice has implications for neuropsychiatric disorders.

Towers AJ, Tremblay MW, Chung L, Li XL, Bey AL, Zhang W, Cao X, Wang X, Wang P, Duffney LJ, Siecinski SK, Xu S, Kim Y, Kong X, Gregory S, Xie W, Jiang YH. Towers AJ, et al. Among authors: wang x, wang p. JCI Insight. 2018 Dec 6;3(23):e120592. doi: 10.1172/jci.insight.120592. JCI Insight. 2018. PMID: 30518695 Free PMC article.

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