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Page 1
Antimicrobial Mechanisms and Clinical Application Prospects of Antimicrobial Peptides.
Li X, Zuo S, Wang B, Zhang K, Wang Y. Li X, et al. Molecules. 2022 Apr 21;27(9):2675. doi: 10.3390/molecules27092675. Molecules. 2022. PMID: 35566025 Free PMC article. Review.
Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and are components of the innate immunity of almost all living things. ...
Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and are components of the innate immunity of …
Targeting EZH2 for cancer therapy: From current progress to novel strategies.
Zeng J, Zhang J, Sun Y, Wang J, Ren C, Banerjee S, Ouyang L, Wang Y. Zeng J, et al. Eur J Med Chem. 2022 Aug 5;238:114419. doi: 10.1016/j.ejmech.2022.114419. Epub 2022 Apr 30. Eur J Med Chem. 2022. PMID: 35569264 Review.
EZH2, the catalytic subunit of PRC2, catalyzes histone H3 lysine 27 (H3K27) trimethylation to induce the agglutination of chromosomes and in turn represses the transcription of the target genes. ...Therefore, targeting EZH2 protein is a promising strategy for cancer treatm …
EZH2, the catalytic subunit of PRC2, catalyzes histone H3 lysine 27 (H3K27) trimethylation to induce the agglutination of chromosomes …
α-Ketoglutaric acid ameliorates hyperglycemia in diabetes by inhibiting hepatic gluconeogenesis via serpina1e signaling.
Yuan Y, Zhu C, Wang Y, Sun J, Feng J, Ma Z, Li P, Peng W, Yin C, Xu G, Xu P, Jiang Y, Jiang Q, Shu G. Yuan Y, et al. Sci Adv. 2022 May 6;8(18):eabn2879. doi: 10.1126/sciadv.abn2879. Epub 2022 May 4. Sci Adv. 2022. PMID: 35507647 Free PMC article.
Mechanistically, we supported that extracellular AKG binds with a purinergic receptor, P2RX4, to initiate the solute carrier family 25 member 11 (SLC25A11)-dependent nucleus translocation of intracellular AKG and subsequently induces demethylation of lysine 27 on histone 3 …
Mechanistically, we supported that extracellular AKG binds with a purinergic receptor, P2RX4, to initiate the solute carrier family 25 membe …
Copper-Catalyzed Difluoroalkylation Reaction.
Dong DQ, Yang SH, Wu P, Wang JZ, Min LH, Yang H, Zhou MY, Wei ZH, Ding CZ, Wang YL, Gao JH, Wang SJ, Wang ZL. Dong DQ, et al. Molecules. 2022 Dec 2;27(23):8461. doi: 10.3390/molecules27238461. Molecules. 2022. PMID: 36500553 Free PMC article. Review.
Fabrication of solid-state nanopores.
Lin K, Chen C, Wang C, Lian P, Wang Y, Xue S, Sha J, Chen Y. Lin K, et al. Nanotechnology. 2022 Apr 20;33(27). doi: 10.1088/1361-6528/ac622b. Nanotechnology. 2022. PMID: 35349996 Review.
Nanopores are valuable single-molecule sensing tools that have been widely applied to the detection of DNA, RNA, proteins, viruses, glycans, etc. ...
Nanopores are valuable single-molecule sensing tools that have been widely applied to the detection of DNA, RNA, proteins, viruses, g …
Production Review of Accelerator-Based Medical Isotopes.
Wang Y, Chen D, Augusto RDS, Liang J, Qin Z, Liu J, Liu Z. Wang Y, et al. Molecules. 2022 Aug 19;27(16):5294. doi: 10.3390/molecules27165294. Molecules. 2022. PMID: 36014532 Free PMC article. Review.
Crystal structure of 8-hex-yloxy-2-[(Z)-2-(naph-thal-en-2-yl)ethen-yl]quinoline.
Liu X, Wang L, Feng Y, Cui D, Liu Z. Liu X, et al. Acta Crystallogr E Crystallogr Commun. 2022 Jul 5;78(Pt 8):770-773. doi: 10.1107/S2056989022006740. eCollection 2022 Aug 1. Acta Crystallogr E Crystallogr Commun. 2022. PMID: 35974831 Free PMC article.
In the title mol-ecule, C(27)H(27)NO, the naphthalene and quinoline groups are both planar and subtend a dihedral angle of 15.47 (7). ...
In the title mol-ecule, C(27)H(27)NO, the naphthalene and quinoline groups are both planar and subtend a dihedral angle of 15. …
1,307 results