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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.
Howard DM, Adams MJ, Clarke TK, Hafferty JD, Gibson J, Shirali M, Coleman JRI, Hagenaars SP, Ward J, Wigmore EM, Alloza C, Shen X, Barbu MC, Xu EY, Whalley HC, Marioni RE, Porteous DJ, Davies G, Deary IJ, Hemani G, Berger K, Teismann H, Rawal R, Arolt V, Baune BT, Dannlowski U, Domschke K, Tian C, Hinds DA; 23andMe Research Team; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Trzaskowski M, Byrne EM, Ripke S, Smith DJ, Sullivan PF, Wray NR, Breen G, Lewis CM, McIntosh AM. Howard DM, et al. Among authors: ward j. Nat Neurosci. 2019 Mar;22(3):343-352. doi: 10.1038/s41593-018-0326-7. Epub 2019 Feb 4. Nat Neurosci. 2019. PMID: 30718901 Free PMC article.
Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci.
Smith DJ, Escott-Price V, Davies G, Bailey ME, Colodro-Conde L, Ward J, Vedernikov A, Marioni R, Cullen B, Lyall D, Hagenaars SP, Liewald DC, Luciano M, Gale CR, Ritchie SJ, Hayward C, Nicholl B, Bulik-Sullivan B, Adams M, Couvy-Duchesne B, Graham N, Mackay D, Evans J, Smith BH, Porteous DJ, Medland SE, Martin NG, Holmans P, McIntosh AM, Pell JP, Deary IJ, O'Donovan MC. Smith DJ, et al. Among authors: ward j. Mol Psychiatry. 2016 Jun;21(6):749-57. doi: 10.1038/mp.2016.49. Epub 2016 Apr 12. Mol Psychiatry. 2016. PMID: 27067015 Free PMC article.
Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci.
Smith DJ, Escott-Price V, Davies G, Bailey ME, Colodro-Conde L, Ward J, Vedernikov A, Marioni R, Cullen B, Lyall D, Hagenaars SP, Liewald DC, Luciano M, Gale CR, Ritchie SJ, Hayward C, Nicholl B, Bulik-Sullivan B, Adams M, Couvy-Duchesne B, Graham N, Mackay D, Evans J, Smith BH, Porteous DJ, Medland SE, Martin NG, Holmans P, McIntosh AM, Pell JP, Deary IJ, O'Donovan MC. Smith DJ, et al. Among authors: ward j. Mol Psychiatry. 2016 Nov;21(11):1644. doi: 10.1038/mp.2016.177. Epub 2016 Sep 13. Mol Psychiatry. 2016. PMID: 27620839 Free PMC article. No abstract available.
Cannabis use and risk of schizophrenia: a Mendelian randomization study.
Vaucher J, Keating BJ, Lasserre AM, Gan W, Lyall DM, Ward J, Smith DJ, Pell JP, Sattar N, Paré G, Holmes MV. Vaucher J, et al. Among authors: ward j. Mol Psychiatry. 2018 May;23(5):1287-1292. doi: 10.1038/mp.2016.252. Epub 2017 Jan 24. Mol Psychiatry. 2018. PMID: 28115737 Free PMC article.
Genome-wide analysis in UK Biobank identifies four loci associated with mood instability and genetic correlation with major depressive disorder, anxiety disorder and schizophrenia.
Ward J, Strawbridge RJ, Bailey MES, Graham N, Ferguson A, Lyall DM, Cullen B, Pidgeon LM, Cavanagh J, Mackay DF, Pell JP, O'Donovan M, Escott-Price V, Smith DJ. Ward J, et al. Transl Psychiatry. 2017 Nov 30;7(11):1264. doi: 10.1038/s41398-017-0012-7. Transl Psychiatry. 2017. PMID: 29187730 Free PMC article.
Seasonality of depressive symptoms in women but not in men: A cross-sectional study in the UK Biobank cohort.
Lyall LM, Wyse CA, Celis-Morales CA, Lyall DM, Cullen B, Mackay D, Ward J, Graham N, Strawbridge RJ, Gill JMR, Ferguson A, Bailey MES, Pell JP, Curtis AM, Smith DJ. Lyall LM, et al. Among authors: ward j. J Affect Disord. 2018 Mar 15;229:296-305. doi: 10.1016/j.jad.2017.12.106. Epub 2018 Jan 4. J Affect Disord. 2018. PMID: 29329063 Free article.
Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort.
Strawbridge RJ, Ward J, Cullen B, Tunbridge EM, Hartz S, Bierut L, Horton A, Bailey MES, Graham N, Ferguson A, Lyall DM, Mackay D, Pidgeon LM, Cavanagh J, Pell JP, O'Donovan M, Escott-Price V, Harrison PJ, Smith DJ. Strawbridge RJ, et al. Among authors: ward j. Transl Psychiatry. 2018 Feb 2;8(1):39. doi: 10.1038/s41398-017-0079-1. Transl Psychiatry. 2018. PMID: 29391395 Free PMC article.
6,101 results