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2020 | 2 |
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An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients.
iScience. 2021 Oct 12;24(11):103221. doi: 10.1016/j.isci.2021.103221. eCollection 2021 Nov 19.
iScience. 2021.
PMID: 34746695
Free PMC article.
Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.
Baxi EG, Thompson T, Li J, Kaye JA, Lim RG, Wu J, Ramamoorthy D, Lima L, Vaibhav V, Matlock A, Frank A, Coyne AN, Landin B, Ornelas L, Mosmiller E, Thrower S, Farr SM, Panther L, Gomez E, Galvez E, Perez D, Meepe I, Lei S, Mandefro B, Trost H, Pinedo L, Banuelos MG, Liu C, Moran R, Garcia V, Workman M, Ho R, Wyman S, Roggenbuck J, Harms MB, Stocksdale J, Miramontes R, Wang K, Venkatraman V, Holewenski R, Sundararaman N, Pandey R, Manalo DM, Donde A, Huynh N, Adam M, Wassie BT, Vertudes E, Amirani N, Raja K, Thomas R, Hayes L, Lenail A, Cerezo A, Luppino S, Farrar A, Pothier L, Prina C, Morgan T, Jamil A, Heintzman S, Jockel-Balsarotti J, Karanja E, Markway J, McCallum M, Joslin B, Alibazoglu D, Kolb S, Ajroud-Driss S, Baloh R, Heitzman D, Miller T, Glass JD, Patel-Murray NL, Yu H, Sinani E, Vigneswaran P, Sherman AV, Ahmad O, Roy P, Beavers JC, Zeiler S, Krakauer JW, Agurto C, Cecchi G, Bellard M, Raghav Y, Sachs K, Ehrenberger T, Bruce E, Cudkowicz ME, Maragakis N, Norel R, Van Eyk JE, Finkbeiner S, Berry J, Sareen D, Thompson LM, Fraenkel E, Svendsen CN, Rothstein JD.
Baxi EG, et al. Among authors: wassie bt.
Nat Neurosci. 2022 Feb;25(2):226-237. doi: 10.1038/s41593-021-01006-0. Epub 2022 Feb 3.
Nat Neurosci. 2022.
PMID: 35115730
Free PMC article.
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Disease related changes in ATAC-seq of iPSC-derived motor neuron lines from ALS patients and controls.
Tsitkov S, Valentine K, Kozareva V, Donde A, Frank A, Lei S; Answer ALS Consortium; E Van Eyk J, Finkbeiner S, Rothstein JD, Thompson LM, Sareen D, Svendsen CN, Fraenkel E.
Tsitkov S, et al.
Nat Commun. 2024 May 2;15(1):3606. doi: 10.1038/s41467-024-47758-8.
Nat Commun. 2024.
PMID: 38697975
Free PMC article.
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A Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small Molecules.
Patel-Murray NL, Adam M, Huynh N, Wassie BT, Milani P, Fraenkel E.
Patel-Murray NL, et al. Among authors: wassie bt.
Sci Rep. 2020 Jan 22;10(1):954. doi: 10.1038/s41598-020-57691-7.
Sci Rep. 2020.
PMID: 31969612
Free PMC article.
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Identifying patterns in amyotrophic lateral sclerosis progression from sparse longitudinal data.
Ramamoorthy D, Severson K, Ghosh S, Sachs K; Answer ALS; Glass JD, Fournier CN; Pooled Resource Open-Access ALS Clinical Trials Consortium; ALS/MND Natural History Consortium; Herrington TM, Berry JD, Ng K, Fraenkel E.
Ramamoorthy D, et al.
Nat Comput Sci. 2022 Sep;2(9):605-616. doi: 10.1038/s43588-022-00299-w. Epub 2022 Sep 8.
Nat Comput Sci. 2022.
PMID: 38177466
Free PMC article.
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Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation.
Smith-Geater C, Hernandez SJ, Lim RG, Adam M, Wu J, Stocksdale JT, Wassie BT, Gold MP, Wang KQ, Miramontes R, Kopan L, Orellana I, Joy S, Kemp PJ, Allen ND, Fraenkel E, Thompson LM.
Smith-Geater C, et al. Among authors: wassie bt.
Stem Cell Reports. 2020 Mar 10;14(3):406-419. doi: 10.1016/j.stemcr.2020.01.015. Epub 2020 Feb 27.
Stem Cell Reports. 2020.
PMID: 32109367
Free PMC article.
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Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements.
Pirhaji L, Milani P, Dalin S, Wassie BT, Dunn DE, Fenster RJ, Avila-Pacheco J, Greengard P, Clish CB, Heiman M, Lo DC, Fraenkel E.
Pirhaji L, et al. Among authors: wassie bt.
Nat Commun. 2017 Sep 20;8(1):623. doi: 10.1038/s41467-017-00353-6.
Nat Commun. 2017.
PMID: 28931805
Free PMC article.
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