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Le Carbone, a charcoal supplement, modulates DSS-induced acute colitis in mice through activation of AMPKα and downregulation of STAT3 and caspase 3 dependent apoptotic pathways.
Afrin MR, Arumugam S, Rahman MA, Karuppagounder V, Sreedhar R, Harima M, Suzuki H, Nakamura T, Miyashita S, Suzuki K, Ueno K, Watanabe K. Afrin MR, et al. Among authors: watanabe k. Int Immunopharmacol. 2017 Feb;43:70-78. doi: 10.1016/j.intimp.2016.10.023. Epub 2016 Dec 12. Int Immunopharmacol. 2017. PMID: 27978459
Modulation of HMGB1 translocation and RAGE/NFκB cascade by quercetin treatment mitigates atopic dermatitis in NC/Nga transgenic mice.
Karuppagounder V, Arumugam S, Thandavarayan RA, Pitchaimani V, Sreedhar R, Afrin R, Harima M, Suzuki H, Nomoto M, Miyashita S, Suzuki K, Nakamura M, Watanabe K. Karuppagounder V, et al. Among authors: watanabe k. Exp Dermatol. 2015 Jun;24(6):418-23. doi: 10.1111/exd.12685. Epub 2015 Mar 25. Exp Dermatol. 2015. PMID: 25739980
Pruni cortex ameliorates skin inflammation possibly through HMGB1-NFκB pathway in house dust mite induced atopic dermatitis NC/Nga transgenic mice.
Watanabe K, Karuppagounder V, Arumugam S, Thandavarayan RA, Pitchaimani V, Sreedhar R, Afrin R, Harima M, Suzuki H, Suzuki K, Nakamura T, Nomoto M, Miyashita S, Fukumoto K, Ueno K. Watanabe K, et al. J Clin Biochem Nutr. 2015 May;56(3):186-94. doi: 10.3164/jcbn.14-75. Epub 2015 Jan 28. J Clin Biochem Nutr. 2015. PMID: 26060348 Free PMC article.
Toki-shakuyaku-san, a Japanese kampo medicine, reduces colon inflammation in a mouse model of acute colitis.
Sreedhar R, Arumugam S, Thandavarayan RA, Giridharan VV, Karuppagounder V, Pitchaimani V, Afrin R, Harima M, Nakamura T, Ueno K, Nakamura M, Suzuki K, Watanabe K. Sreedhar R, et al. Among authors: watanabe k. Int Immunopharmacol. 2015 Dec;29(2):869-875. doi: 10.1016/j.intimp.2015.08.029. Epub 2015 Sep 4. Int Immunopharmacol. 2015. PMID: 26344429
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