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Alterations of PINK1-PRKN signaling in mice during normal aging.
Baninameh Z, Watzlawik JO, Hou X, Richardson T, Kurchaba NW, Yan T, Di Florio DN, Fairweather D, Kang L, Nguyen JH, Kanekiyo T, Dickson DW, Noda S, Sato S, Hattori N, Goldberg MS, Ganley IG, Stauch KL, Fiesel FC, Springer W. Baninameh Z, et al. Among authors: watzlawik jo. bioRxiv [Preprint]. 2024 May 1:2024.04.29.591753. doi: 10.1101/2024.04.29.591753. bioRxiv. 2024. PMID: 38746191 Free PMC article. Preprint.
Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in cells and tissue.
Watzlawik JO, Hou X, Richardson T, Lewicki SL, Siuda J, Wszolek ZK, Cook CN, Petrucelli L, DeTure M, Dickson DW, Antico O, Muqit MMK, Fishman JB, Pirani K, Kumaran R, Polinski NK, Fiesel FC, Springer W. Watzlawik JO, et al. bioRxiv [Preprint]. 2024 Jan 16:2024.01.15.575715. doi: 10.1101/2024.01.15.575715. bioRxiv. 2024. PMID: 38293125 Free PMC article. Preprint.
Basal activity of PINK1 and PRKN in cell models and rodent brain.
Watzlawik JO, Fiesel FC, Fiorino G, Bustillos BA, Baninameh Z, Markham BN, Hou X, Hayes CS, Bredenberg JM, Kurchaba NW, Fričová D, Siuda J, Wszolek ZK, Noda S, Sato S, Hattori N, Prasad AA, Kirik D, Fox HS, Stauch KL, Goldberg MS, Springer W. Watzlawik JO, et al. Autophagy. 2023 Dec 2:1-12. doi: 10.1080/15548627.2023.2286414. Online ahead of print. Autophagy. 2023. PMID: 38041584
A common pathway for detergent-assisted oligomerization of Aβ42.
Muhammedkutty FNK, Prasad R, Gao Y, Sudarshan TR, Robang AS, Watzlawik JO, Rosenberry TL, Paravastu AK, Zhou HX. Muhammedkutty FNK, et al. Among authors: watzlawik jo. Commun Biol. 2023 Nov 21;6(1):1184. doi: 10.1038/s42003-023-05556-w. Commun Biol. 2023. PMID: 37989804 Free PMC article.
Genome-wide association study identifies APOE and ZMIZ1 variants as mitophagy modifiers in Lewy body disease.
Hou X, Heckman MG, Fiesel FC, Koga S, Soto-Beasley AI, Watzlawik JO, Zhao J, Valentino RR, Johnson PW, White LJ, Quicksall ZS, Reddy JS, Bras J, Guerreiro R, Zhao N, Bu G, Dickson DW, Ross OA, Springer W. Hou X, et al. Among authors: watzlawik jo. medRxiv [Preprint]. 2023 Oct 16:2023.10.16.23297100. doi: 10.1101/2023.10.16.23297100. medRxiv. 2023. PMID: 37905059 Free PMC article. Preprint.
Interplay of Impaired Cellular Bioenergetics and Autophagy in PMM2-CDG.
Ligezka AN, Budhraja R, Nishiyama Y, Fiesel FC, Preston G, Edmondson A, Ranatunga W, Van Hove JLK, Watzlawik JO, Springer W, Pandey A, Morava E, Kozicz T. Ligezka AN, et al. Among authors: watzlawik jo. Genes (Basel). 2023 Aug 4;14(8):1585. doi: 10.3390/genes14081585. Genes (Basel). 2023. PMID: 37628636 Free PMC article.
Substitution of PINK1 Gly411 modulates substrate receptivity and turnover.
Fiesel FC, Fričová D, Hayes CS, Coban MA, Hudec R, Bredenberg JM, Broadway BJ, Markham BN, Yan T, Boneski PK, Fiorino G, Watzlawik JO, Hou X, McCarty AM, Lewis-Tuffin LJ, Zhong J, Madden BJ, Ordureau A, An H, Puschmann A, Wszolek ZK, Ross OA, Harper JW, Caulfield TR, Springer W. Fiesel FC, et al. Among authors: watzlawik jo. Autophagy. 2023 Jun;19(6):1711-1732. doi: 10.1080/15548627.2022.2151294. Epub 2022 Dec 5. Autophagy. 2023. PMID: 36469690 Free PMC article.
Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples.
Watzlawik JO, Hou X, Fricova D, Ramnarine C, Barodia SK, Gendron TF, Heckman MG, DeTure M, Siuda J, Wszolek ZK, Scherzer CR, Ross OA, Bu G, Dickson DW, Goldberg MS, Fiesel FC, Springer W. Watzlawik JO, et al. Autophagy. 2021 Sep;17(9):2613-2628. doi: 10.1080/15548627.2020.1834712. Epub 2020 Oct 28. Autophagy. 2021. PMID: 33112198 Free PMC article.
31 results